The integrin LFA-1 is crucial for T cell entry into mammalian lymph nodes and tissues, and
for promoting interactions with antigen-presenting cells (APCs). However, it is increasingly …

Group 1 innate lymphoid cells (ILC1s) are cytotoxic and interferon gamma-producing
lymphocytes lacking antigen-specific receptors, which include ILC1s and natural killer (NK) …

Recent advances in single-cell immune profiling have enabled the simultaneous
measurement of transcriptome and T cell receptor (TCR) sequences, offering great potential …

Integrins are a group of heterodimers consisting of α and β subunits that mediate a variety of
physiological activities of immune cells, including cell migration, adhesion, proliferation …

Disclosures: K. Tsai reported personal fees from Regeneron, grants from Array/Pfizer, grants
from Replimune, and grants from Oncosec outside the submitted work. M. Rosenblum …

Immune checkpoint inhibitors are used for treating patients with metastatic melanoma. Since
the response to treatment is variable, biomarkers are urgently needed to identify patients …

Long non-coding RNAs (lncRNAs) could modulate expression of immune checkpoints
(ICPs) in tumor-immune. However, precise functions in immunity and potential for predicting …

Augmenting adaptive immunity is a critical goal for developing next-generation cancer
therapies. T and B cells infiltrating the tumor dramatically influence cancer progression …

The T cell receptor (TCR) repertoire is an extraordinarily diverse collection of TCRs essential
for maintaining the body's homeostasis and response to threats. In this study, we compiled …

The accumulation of hyaluronan oligosaccharides (oHA) in colorectal cancer (CRC) is
closely related to tumor metastasis, but the underlying mechanism remains unclear. In this …