The comet assay as a tool for human biomonitoring studies: the ComNet project

A Collins, G Koppen, V Valdiglesias, M Dusinska… - … research/reviews in …, 2014 - Elsevier
The comet assay is widely used in human biomonitoring to measure DNA damage as a
marker of exposure to genotoxic agents or to investigate genoprotective effects. Studies …

Measurement of DNA damage with the comet assay in high-prevalence diseases: current status and future directions

P Møller, H Stopper, AR Collins - Mutagenesis, 2020 - academic.oup.com
The comet assay is widely used in studies on genotoxicity testing, human biomonitoring and
clinical studies. The simple version of the assay detects a mixture of DNA strand breaks and …

[HTML][HTML] Dietary reference values of individual micronutrients and nutriomes for genome damage prevention: current status and a road map to the future

MF Fenech - The American journal of clinical nutrition, 2010 - Elsevier
Damage to the genome is recognized as a fundamental cause of developmental and
degenerative diseases. Several micronutrients play an important role in protecting against …

Oxidized extracellular DNA as a stress signal in human cells

AV Ermakov, MS Konkova, SV Kostyuk… - Oxidative medicine …, 2013 - Wiley Online Library
The term “cell‐free DNA”(cfDNA) was recently coined for DNA fragments from
plasma/serum, while DNA present in in vitro cell culture media is known as extracellular …

Stromal vascular fraction restores vasodilatory function by reducing oxidative stress in aging-induced coronary microvascular disease

EP Tracy, M Dukes, G Rowe, JE Beare… - Antioxidants & redox …, 2023 - liebertpub.com
Aims: The objective of this study is to identify mechanisms for adipose stromal vascular
fraction's (SVF) restorative effects on vasodilation in aging-induced coronary microvascular …

Oxidative stress is associated with genetic polymorphisms in one-carbon metabolism in coronary artery disease

SV Vijaya Lakshmi, SM Naushad… - Cell biochemistry and …, 2013 - Springer
In view of growing body of evidence favouring the association of aberrations in one-carbon
metabolism and oxidative stress in the aetiology of coronary artery disease (CAD), we …

Polyphenol compounds as antioxidants for disease prevention: reactive oxygen species scavenging, enzyme regulation, and metal chelation mechanisms in E. coli …

HC Wang, JL Brumaghim - Oxidative stress: diagnostics …, 2011 - ACS Publications
Polyphenol antioxidants are abundant in the diet and have the potential to prevent diseases
caused by oxidative stress, including neurodegenerative and cardiovascular diseases …

[PDF][PDF] The role of oxidative DNA damage and GSTM1, GSTT1, and hOGG1 gene polymorphisms in coronary artery disease risk.

E Kadıoğlu, G Taçoy, E Özçağlı… - Anatolian Journal of …, 2016 - jag.journalagent.com
Objective: Atherosclerotic coronary artery disease (CAD) appears to be a multifactorial
process caused by the interaction of environmental risk factors with multiple predisposing …

Selenium supplementation does not improve vascular responsiveness in healthy North American men

WC Hawkes, LJ Laslett - American Journal of Physiology …, 2009 - journals.physiology.org
Selenium is an essential trace nutrient required for the synthesis of selenoproteins such as
glutathione peroxidase and thioredoxin reductase, the major forms of selenium in the …

DNA damage in children and adolescents with cardiovascular disease risk factors

M Kliemann, D Prá, LL Müller, L Hermes… - Anais da Academia …, 2012 - SciELO Brasil
The risk of developing cardiovascular disease (CVD) is related to lifestyle (eg diet, physical
activity and smoking) as well as to genetic factors. This study aimed at evaluating the …