Both genetic background and environmental factors, very probably viruses, appear to play a
role in the etiology of multiple sclerosis (MS). Lessons from viral experimental models …

Theiler's virus causes a persistent and demyelinating infection of the central nervous system
of the mouse, which is one of the best animal models to study multiple sclerosis. This review …

A number of viruses can initiate central nervous system (CNS) diseases that include
demyelination as a major feature of neuropathology. In humans, the most prominent …

Theiler's virus is a picornavirus of mouse which Closes U ac UK encephalomyelitis followed
by a persistent infection of the white matter of the spinal cord with chronic inflammation and …

Pertussis toxin (PTX) is a potent ancillary adjuvant used to elicit several different
autoimmune diseases, including experimental allergic encephalomyelitis (EAE). To …

Theiler's virus persistently infects the white matter of the spinal cord in susceptible strains of
mice. This infection is associated with inflammation and primary demyelination and is …

Theiler's virus is a picornavirus of mouse which causes an acute encephalomyelitis followed
by a persistent infection of the white matter resulting in chronic inflammation and …

Theiler's virus, a picornavirus, persists for life in the central nervous system of mouse and
causes a demyelinating disease that is a model for multiple sclerosis. The virus infects …

An overview of the Theiler's model of demyelinating disease 3. Multiple Sclerosis–the short
course 4. Axonal injury in demyelinating disease. Does demyelination really matter? 4.1 …

ABSTRACT H-2b mice are resistant to persistent infection of the central nervous system by
Theiler's virus. They clear the infection 7 to 10 days after intracranial inoculation. Resistance …