In recent decades many advances have occurred in the understanding of the role of
cytokines in breast cancer. New signalling pathways of interleukin (IL)-1 family, IL-6, IL-11, IL …

Short tandem repeats (STRs) have been implicated in a variety of complex traits in humans.
However, genome-wide studies of the effects of STRs on gene expression thus far have had …

Emerging evidence has shown multiple roles of the tumor microenvironment (TME)
components, specifically the extracellular matrix (ECM), in breast cancer development …

Angiogenesis is the process by which new blood vessels are formed from existing vessels.
Mammalian populations harbor genetic variations that alter angiogenesis. Some of these …

Background-Sporadic breast cancer like many other cancers is proposed to be a
manifestation of abnormal genetic and epigenetic changes. For the past decade our …

Dysregulation or inhibition of apoptosis favors cancer and many other diseases.
Understanding of the network interaction of the genes involved in apoptotic pathway …

Recently, TRAIL function has been elucidated beyond its known classical role of mediating
cellular homeostasis and immune surveillance against transformed cells. Here, we show …

Background Esophageal squamous cell carcinoma (ESCC) as the most prominent type of
esophageal cancer (EC) in developing countries encompasses a substantial contribution of …

The pathogenesis of recurrent oral ulcers (ROU) is complex, with a long duration of illness
and challenging to cure. According to traditional Chinese medicine (TCM),” heat …

Pro-inflammatory cytokines IFNγ and IFNα function through their cellular receptors IFNγR1
and IFNαR1, respectively to mediate immune processes during malaria infection. A total of …