[HTML][HTML] Rotavirus interactions with host intestinal epithelial cells

JO Amimo, SA Raev, J Chepngeno… - Frontiers in …, 2021 - frontiersin.org
Rotavirus (RV) is the foremost enteric pathogen associated with severe diarrheal illness in
young children (< 5years) and animals worldwide. RV primarily infects mature enterocytes in …

Current advances in structure–function relationships and dose-dependent effects of human milk oligosaccharides

J Wang, MS Chen, RS Wang, JQ Hu, S Liu… - Journal of Agricultural …, 2022 - ACS Publications
HMOs (human milk oligosaccharides) are the third most important nutrient in breast milk. As
complex glycans, HMOs play an important role in regulating neonatal intestinal immunity …

[HTML][HTML] The role of host glycobiology and gut microbiota in rotavirus and norovirus infection, an update

N Peña-Gil, C Santiso-Bellón… - International journal of …, 2021 - mdpi.com
Rotavirus (RV) and norovirus (NoV) are the leading causes of acute gastroenteritis (AGE)
worldwide. Several studies have demonstrated that histo-blood group antigens (HBGAs) …

Sodium butyrate protects against rotavirus-induced intestinal epithelial barrier damage by activating AMPK-Nrf2 signaling pathway in IPEC-J2 cells

X Dong, Y Wang, X Zhu, L Shen, L Chen, L Niu… - International Journal of …, 2023 - Elsevier
Rotavirus (RV) mainly infects intestinal epithelial cells, which leads to diarrhea in newborn
piglets with dysfunction in the intestinal mucosal mechanical barrier. Sodium butyrate (SB) is …

Intestinal mucin-type O-glycans: the major players in the host-bacteria-rotavirus interactions

SA Raev, JO Amimo, LJ Saif, AN Vlasova - Gut Microbes, 2023 - Taylor & Francis
Rotavirus (RV) causes severe diarrhea in young children and animals worldwide. Several
glycans terminating in sialic acids (SAs) and histo-blood group antigens (HBGAs) on …

[HTML][HTML] Rotavirus C replication in porcine intestinal enteroids reveals roles for cellular cholesterol and sialic acids

Y Guo, S Raev, MK Kick, M Raque, LJ Saif, AN Vlasova - Viruses, 2022 - mdpi.com
Rotaviruses (RVs) are a significant cause of severe diarrheal illness in infants and young
animals, including pigs. Group C rotavirus (RVC) is an emerging pathogen increasingly …

Re-examining rotavirus innate immune evasion: potential applications of the reverse genetics system

A Antia, AN Pinski, S Ding - MBio, 2022 - Am Soc Microbiol
Rotaviruses represent one of the most successful pathogens in the world, with high
infectivity and efficient transmission between the young of many animal species, including …

Zoonotic and reverse zoonotic transmission of viruses between humans and pigs

HA Glud, S George, K Skovgaard, LE Larsen - Apmis, 2021 - Wiley Online Library
Humans and pigs share a close contact relationship, similar biological traits, and one of the
highest estimated number of viruses compared to other mammalian species. The …

Glycan-mediated interactions between bacteria, rotavirus and the host cells provide an additional mechanism of antiviral defence

SA Raev, AM Omwando, Y Guo… - Beneficial …, 2022 - wageningenacademic.com
Limited efficacy of rotavirus (RV) vaccines in children in developing countries and in animals
remains a significant problem necessitating further search for additional approaches to …

[HTML][HTML] Differential transcriptome response following infection of porcine ileal enteroids with species A and C rotaviruses

SA Raev, M Raque, MK Kick, LJ Saif, AN Vlasova - Virology Journal, 2023 - Springer
Abstract Background Rotavirus C (RVC) is the major causative agent of acute gastroenteritis
in suckling piglets, while most RVAs mostly affect weaned animals. Besides, while most RVA …