MicroRNA-34 (miR-34) is a master regulator of tumor suppression. It is downregulated in
numerous cancers and inhibits malignant growth by repressing genes involved in various …

In recent years, microRNAs (miRNAs) have been identified as mediators of tumour
suppression and stress responses exerted by the p53 tumour suppressor. p53-regulated …

The most important biological function of exosomes is their possible use as biomarkers in
clinical diagnosis. Compared with biomarkers identified in conventional specimens such as …

The age-related vasculature alteration is the prominent risk factor for vascular diseases
(VD), namely, atherosclerosis, abdominal aortic aneurysm, vascular calcification (VC) and …

DNA methylation plays a key role in the silencing of numerous cancer-related genes,
thereby affecting a number of vital cellular processes, including the cell cycle checkpoint …

ABSTRACT microRNAs (miRNAs) and DNA methylation are the 2 epigenetic modifications
that have emerged in recent years as the most critical players in the regulation of gene …

Abstract MicroRNA-34 (miR-34) plays central roles in human diseases, especially cancers.
Inactivation of miR-34 is detected in cancer cell lines and tumor tissues versus normal …

MicroRNAs (miRNAs) play pivotal roles in numerous biological processes, and their
dysregulation is a common feature of human cancer. Thanks to recent advances in the …

Since the first microRNA (miRNA) was discovered, a lot of studies have confirmed the
associations between miRNAs and human complex diseases. Besides, obtaining and taking …

The incidence of gastroesophageal cancers is increasing each year, but despite much
research, their molecular mechanisms are incompletely understood. microRNAs (miRNAs) …