Herpes simplex virus evasion of early host antiviral responses

EI Tognarelli, TF Palomino, N Corrales… - Frontiers in cellular …, 2019 - frontiersin.org
Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) have co-evolved with humans for
thousands of years and are present at a high prevalence in the population worldwide. HSV …

The enigmatic nature of the TCR-pMHC interaction: implications for CAR-T and TCR-T engineering

DV Shevyrev, VP Tereshchenko… - International Journal of …, 2022 - mdpi.com
The interaction of the T-cell receptor (TCR) with a peptide in the major histocompatibility
complex (pMHC) plays a central role in the adaptive immunity of higher chordates. Due to …

Is TCR/pMHC affinity a good estimate of the T-cell response? An answer based on predictions from 12 phenotypic models

J Gálvez, JJ Gálvez, P García-Peñarrubia - Frontiers in immunology, 2019 - frontiersin.org
On the T-cell surface the TCR is the only molecule that senses antigen, and the engagement
of TCR with its specific antigenic peptide (agonist)/MHC complex (pMHC) is determined by …

TAOK3, a Regulator of LCK–SHP-1 Crosstalk during TCR Signaling

JVS Ormonde, Y Nie, J Madrenas - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Signaling from the T cell receptor for antigen turns on the physiological response of a T cell.
The canonical TCR signaling pathway relies on early activation of the Src kinase LCK. This …

Immunobiochemical Reconstruction of Influenza Lung Infection—Melanoma Skin Cancer Interactions

EV Nikolaev, A Zloza, ED Sontag - Frontiers in immunology, 2019 - frontiersin.org
It was recently reported that acute influenza infection of the lung promoted distal melanoma
growth in the dermis of mice. Melanoma-specific CD8+ T cells were shunted to the lung in …

Regulation of T cell activation by thousand-and-one amino acid kinase 3

J Vitor Silva Ormonde - 2020 - escholarship.mcgill.ca
Canonical signaling from the T cell receptor triggers the physiological response of a T cell.
The canonical TCR signaling pathway relies on activation of the Src kinase LCK, which is …

[PDF][PDF] TCR-pMHC interactions

AG Zucco - researchgate.net
Abstract The recognition of Major Histocompatibility Complexes presenting linear peptides
by T-Cell receptors is a key event in adaptive immunity. These interactions are MHC …

[引用][C] THE ENZYME HEME OXYGENASE-1 INHIBITS HERPES SIMPLEX VIRUS REPLICATIVE CYCLE AND PROTECTS AGAINST INFECTIOUS SKIN DISEASE IN …

FJI Irribarra - 2022 - Pontificia Universidad Católica de …