[HTML][HTML] Recent data on the cerebellum require new models and theories

Y Zang, E De Schutter - Current Opinion in Neurobiology, 2023 - Elsevier
The cerebellum has been a popular topic for theoretical studies because its structure was
thought to be simple. Since David Marr and James Albus related its function to motor skill …

Fundamental processes in sensorimotor learning: Reasoning, refinement, and retrieval

JS Tsay, HE Kim, SD McDougle, JA Taylor, A Haith… - Elife, 2024 - elifesciences.org
Motor learning is often viewed as a unitary process that operates outside of conscious
awareness. This perspective has led to the development of sophisticated models designed …

Excitatory nucleo-olivary pathway shapes cerebellar outputs for motor control

X Wang, Z Liu, M Angelov, Z Feng, X Li, A Li… - Nature …, 2023 - nature.com
The brain generates predictive motor commands to control the spatiotemporal precision of
high-velocity movements. Yet, how the brain organizes automated internal feedback to …

Diversity of the nature of input and output signals in the cerebellum suggests a diversity of function

JJO de Xivry, J Diedrichsen - Current Opinion in Behavioral Sciences, 2024 - Elsevier
Highlights•The local circuitry is invariant across a range of functional cerebellar regions.•The
nature of the inputs, and the function of the output, varies widely across similar tasks.•This …

Complex spikes perturb movements and reveal the sensorimotor map of Purkinje cells

SZ Muller, JS Pi, P Hage, MA Fakharian… - Current Biology, 2023 - cell.com
Computations that are performed by the cerebellar cortex are transmitted via simple spikes
of Purkinje cells (P-cells) to downstream structures, but because P-cells are many synapses …

Implantable nanophotonic neural probes for integrated patterned photostimulation and electrophysiology recording

FD Chen, HM Chameh, M Movahed, H Wahn, X Mu… - bioRxiv, 2023 - biorxiv.org
Optogenetics has transformed neuroscience by allowing precise manipulation of neural
circuits with light [–]. However, a central difficulty has been to deliver spatially shaped light …

Striatal dopamine contributions to skilled motor learning

CD Phillips, AT Hodge, CC Myers… - Journal of …, 2024 - Soc Neuroscience
Coordinated multi-joint limb and digit movements-“manual dexterity”-underlie both
specialized skills (eg, playing the piano) and more mundane tasks (eg, tying shoelaces) …

A cerebellar population coding model for sensorimotor learning

T Wang, RB Ivry - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
The cerebellum is crucial for sensorimotor adaptation, using error information to keep the
sensorimotor system well-calibrated. Here we introduce a population-coding model to …

[HTML][HTML] A novel biomechanical model of the mouse forelimb predicts muscle activity in optimal control simulations of reaching movements

JI Gilmer, SK Coltman, G Cuenu, JR Hutchinson… - …, 2024 - pmc.ncbi.nlm.nih.gov
Mice are key model organisms in neuroscience and motor systems physiology. Fine motor
control tasks performed by mice have become widely used in assaying neural and …

Highlights from the 32nd Annual Meeting of the Society for the Neural Control of Movement

K Love, D Cao, JC Chang… - Journal of …, 2024 - journals.physiology.org
34 The Society of Neural Control of Movement (NCM) held its 32nd annual meeting in 35
beautiful Victoria, British Columbia, Canada in April of 2023. Over 350 researchers, 36 …