Appropriate Treatment Intensity for Diffuse Large B-Cell Lymphoma in the Older Population: A Review of the Literature

S Yamasaki - Hematology Reports, 2024 - mdpi.com
Most patients with diffuse large B-cell lymphoma (DLBCL) are> 65 years of age, with the
number of patients expected to increase in the coming years. A comprehensive geriatric …

The elderly prognostic index predicts early mortality in older patients with diffuse large B‐cell lymphoma. An ad hoc analysis of the elderly project by the Fondazione …

E Cencini, A Tucci, B Puccini, F Cavallo… - Hematological …, 2023 - Wiley Online Library
Abstract The Elderly Prognostic Index (EPI) is based on the integration of a simplified
geriatric assessment, hemoglobin levels and International Prognostic Index and has been …

Comorbidities and sex differences in causes of death among mantle cell lymphoma patients–a nationwide population‐based cohort study

I Glimelius, KE Smedby, S Eloranta… - British Journal of …, 2020 - Wiley Online Library
The prognosis for mantle cell lymphoma (MCL) remains poor. Our aim was to assess the
impact of comorbidities on survival and causes of death. For 1,385 MCL patients (1,009 …

Is bendamustine-rituximab a reasonable treatment in selected older patients with diffuse large B cell lymphoma? Results from a multicentre, retrospective study

V Zeremski, K Jentsch-Ullrich, C Kahl, M Mohren… - Annals of …, 2019 - Springer
Despite bendamustine-rituximab (BR) showed disappointing efficacy in diffuse large B cell
lymphoma (DLBCL), it is still occasionally used as first-line treatment in older DLBCL …

The metronomic all-oral DEVEC is an effective schedule in elderly patients with diffuse large b-cell lymphoma

MC Cox, S Pelliccia, L Marcheselli, R Battistini… - Investigational New …, 2019 - Springer
Summary Metronomic-chemotherapy (M-CHT) has been rarely assessed in non-Hodgkin-
lymphoma (NHL). Therefore, in 2011 we started experimenting a new all-oral M-CHT …

Clinical outcomes after incomplete cycles of R-CHOP for diffuse large B-cell lymphoma: 10 years' real-world experience in a single institute

J Yoon, KH Kim, JS Kim, JM Byun, J Hong, DY Shin… - Annals of …, 2023 - Springer
Although the current standard of care for diffuse large B-cell lymphoma (DLBCL) is six cycles
of rituximab/cyclophosphamide/doxorubicin/vincristine/prednisolone combination …

The Haemato‐Oncology Frailty (HOF) score to assess frailty in lymphoma

H Ramdany, T Lofaro, S Deplano - European Journal of …, 2024 - Wiley Online Library
Morbidity and mortality during chemotherapy in older adults with haematological malignancy
can be unpredictable. The Haemato‐Oncology Frailty (HOF) score was previously found to …

[HTML][HTML] Impact of relative dose intensity of R-CCOP regimen in elderly patients with diffuse large B-cell lymphoma in China

H Gao, Y Liu, Y Xu, L Mi, C Zhang, X Wang… - Journal of the Formosan …, 2022 - Elsevier
Background The actual relative dose intensity (RDI) of the attenuated R-CCOP regimen
(rituximab, cytoxan, pegylated liposomal doxorubicin [PLD], vincristine, and prednisone) has …

[HTML][HTML] Oral chemotherapy application in elderly patients with diffuse large B-cell lymphoma: An alternative regimen in retrospective analysis

PH Liao, CY Kuo, MC Ma, CK Liao, SN Pei… - Journal of …, 2022 - ncbi.nlm.nih.gov
Background A combination of rituximab, cyclophosphamide, doxorubicin, vincristine, and
prednisone (R-CHOP) is considered the standard treatment for diffuse large B-cell …

CD20-negative primary middle ear diffuse large B-cell lymphoma coexpressing MYC and BCL-2 secondary to acute lymphoblastic leukemia: A case report

C Ding, Y Huang, M Shi, B Nie, Y Li, K Wu, J Yang… - Medicine, 2019 - journals.lww.com
Interventions: Chemotherapy. Outcomes: The patient eventually gave up and died of severe
infection. Lessons: Although intensive chemotherapy has markedly improved the survival of …