Cancer is still among the leading health issues today, considering the cost, effectiveness,
complexity of detection/treatment modalities and survival rates. One of the most important …

Non-destructive fluorophore diffusion across cell membranes to provide an unbiased
fluorescence intensity readout is critical for quantitative imaging applications in live cells and …

Mitochondria play important roles in diverse cellular processes such as energy production,
cellular metabolism, and apoptosis to promote cell death. To investigate mitochondria …

By taking advantage of a unique mechanism of aggregation-induced emission (AIE)
phenomena, AIE luminogens (AIEgens) have been provided as a solution to overcome the …

Ribosomal RNA (rRNA) plays a key role in protein synthesis and ribosomal biogenesis. The
exclusively used commercial dye for RNA staining is SYTO RNASelect which works in fixed …

Elucidation of biological phenomena requires imaging of microenvironments in vivo.
Although the seamless visualization of in vivo hypoxia from the level of whole-body to single …

Mitochondria, as the powerhouse of most cells, are not only responsible for the generation of
adenosine triphosphate (ATP) but also play a decisive role in the regulation of apoptotic cell …

Mitochondrial probe SiRPFA was synthesized by attaching a long perfluoroalkyl chain on Si-
rhodamine cationic dye. High lipophilicity endowed SiRPFA with mitochondrial membrane …

Normally, small-molecule fluorescent probes dependent on the mitochondrial membrane
potential (MMP) are invalid for fixed cells and tissues, which limits their clinical applications …

Mitochondria, pivotal organelles responsible for cellular energy production and behavioral
regulation, play a crucial role in various diseases, notably cancer. Mitochondria-targeting …