[HTML][HTML] Protective effects of curcumin against traumatic brain injury

D Khayatan, SM Razavi, ZN Arab, AH Niknejad… - Biomedicine & …, 2022 - Elsevier
Neuroinflammation is a key pathophysiological mechanism implicated in the
neurodegenerative condition. One such condition implicating neuroinflammation is traumatic …

Colloidal therapeutics in the management of traumatic brain injury: Portray of biomarkers and drug-targets, preclinical and clinical pieces of evidence and future …

S Arya, D Bahuguna, G Bajad, S Loharkar… - Colloids and Surfaces B …, 2023 - Elsevier
Complexity associated with the aberrant physiology of traumatic brain injury (TBI) makes its
therapeutic targeting vulnerable. The underlying mechanisms of pathophysiology of TBI are …

Traumatic brain injury-associated epigenetic changes and the risk for neurodegenerative diseases

P Smolen, PK Dash, JB Redell - Frontiers in Neuroscience, 2023 - frontiersin.org
Epidemiological studies have shown that traumatic brain injury (TBI) increases the risk for
developing neurodegenerative diseases (NDs). However, molecular mechanisms that …

[HTML][HTML] Network pharmacology and topological analysis on tibolone metabolites and their molecular mechanisms in traumatic brain injury

GE Barreto, J Gonzalez, D Ramírez - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Traumatic brain injury (TBI) is a pathology of great social impact, affecting millions of people
worldwide. Despite the scientific advances to improve the management of TBI in recent …

Comparison of antioxidant capacity and network pharmacology of phloretin and phlorizin against neuroinflammation in traumatic brain injury

KK Ongay, D Granato, GE Barreto - Molecules, 2023 - mdpi.com
Neuroinflammation is a hallmark of traumatic brain injury (TBI)'s acute and chronic phases.
Despite the medical and scientific advances in recent years, there is still no effective …

[HTML][HTML] Role of statins in regulating molecular pathways following traumatic brain injury: A system pharmacology study

A Mahmoudi, S Heydari, YV Markina, GE Barreto… - Biomedicine & …, 2022 - Elsevier
Traumatic brain injury (TBI) is a serious disorder with debilitating physical and psychological
complications. Previous studies have indicated that genetic factors have a critical role in …

[HTML][HTML] Jiuzhuan Huangjing Pills alleviate fatigue by preventing energy metabolism dysfunctions in mitochondria

P Shen, W Yu, B Deng, T Ao, Y Tao, Z Ni… - Journal of Functional …, 2024 - Elsevier
Fatigue exerts a profound impact on human health. Jiuzhuan Huangjing Pills (JHP),
comprising two functional foods, exhibits homology of medicine and food. In this study, we …

[HTML][HTML] Exploration of novel ligands to target CC Motif Chemokine Receptor 2 (CCR2) as a promising pharmacological treatment against traumatic brain injury

KR Sachdev, KJ Lynch, GE Barreto - Biomedicine & Pharmacotherapy, 2022 - Elsevier
It is widely reported that the overexpression of the CC Motif Chemokine Receptor 2 (CCR2)
has negative implications in neuroinflammatory diseases such as traumatic brain injury …

Small Molecule Drug C381 Attenuates Brain Vascular Damage Following Repetitive Mild Traumatic Injury

L Li, A Nguyen, B Zhao, R Vest, L Yerra, B Sun… - Neurotrauma …, 2024 - liebertpub.com
Traumatic brain injury (TBI) remains a significant public health concern, with no effective
therapeutic interventions to ameliorate the enduring consequences. The prevailing …