Advanced drug delivery systems rely on the availability of biocompatible materials.
Moreover, biodegradability is highly desirable in the design of those systems. Consequently …

In pharmaceutical research and development, various new chemical entities (NCE) are
found to be poorly water-soluble. Therefore, solubility enhancement, a key factor for higher …

Supercritical anti-solvent (SAS) method is a solvent-free approach where supercritical
carbon dioxide (SC-CO 2) is used as anti-solvent and one can control the output particle …

Presenting breakthrough research pertinent to scientists in a wide range of disciplines-from
medicine and biotechnology to cosmetics and pharmacy-this Second Edition provides …

Nanoparticles from commercial kraft lignin were developed using a facile, one pot green
technology of a compressed CO2 antisolvent. N, N-Dimethylformamide (DMF) was …

In the pharmaceutical industry, an even greater number of products are in the form of
particulate solids. Their formation, formulation and the control of their user properties are still …

The interest of the use of supercritical fluids, especially supercritical CO2, for particle
engineering over the last years has received attention from the pharmaceutical industry …

In this work, amorphous atorvastatin calcium nanoparticles were successfully prepared
using the supercritical antisolvent (SAS) process. The effect of process variables on particle …

Supercritical fluid (SCF) processing methods possess advantages over standard processing
methods for the production of scaffolds for use in tissue engineering. Advantages include the …

Supercritical fluids possess the unique properties of behaving like liquids and gases, above
their critical point. Supercritical fluid technology has recently emerged as a green and novel …