The Role of Peptides in Asthma–Obesity Phenotype

E Russjan - International Journal of Molecular Sciences, 2024 - mdpi.com
The co-occurrence of asthma and obesity is becoming an increasingly common health
problem. It became clear that both diseases are closely related, since overweight/obesity are …

Role of Lipid Profile and Its Relative Ratios (Cholesterol/HDL‐C, Triglyceride/HDL‐C, LDL‐C/HDL‐C, WBC/HDL‐C, and FBG/HDL‐C) on Admission Predicts In …

J Mohammadshahi, H Ghobadi, G Matinfar… - Journal of …, 2023 - Wiley Online Library
Background. Lipid profile and its related ratios such as total cholesterol (TC), low‐density
lipoprotein‐cholesterol (LDL‐C), triglyceride (TG), high‐density lipoprotein‐cholesterol (HDL …

Obesity-associated airway Hyperresponsiveness: Mechanisms Underlying Inflammatory Markers and Possible Pharmacological Interventions

MP Pathak, P Patowary… - … Metabolic & Immune …, 2024 - ingentaconnect.com
Obesity is rapidly becoming a global health problem affecting about 13% of the world's
population affecting women and children the most. Recent studies have stated that obese …

Crocin attenuates inflammation of lung tissue in ovalbumin‐sensitized mice by altering the expression of endoplasmic reticulum stress markers

MR Aslani, M Amani, N Masrori, MH Boskabady… - Biofactors, 2022 - Wiley Online Library
Endoplasmic reticulum (ER) stress plays a pivotal role in the pathogenesis of asthma. The
present study aimed to investigate the reducing or suppressing effects of crocin in ovalbumin …

Altered gene expression levels of IL-17/TRAF6/MAPK/USP25 axis and pro-inflammatory cytokine levels in lung tissue of obese ovalbumin-sensitized rats

MR Aslani, A Sharghi, MH Boskabady, H Ghobadi… - Life Sciences, 2022 - Elsevier
Aims The association between asthma and obesity has been shown but its accurate
mechanism is unknown. In the current study, we sought to investigate the gene expression …

Effect of high fat diet on NF‐кB microRNA146a negative feedback loop in ovalbumin‐sensitized rats

G Akhavanakbari, B Babapour, MR Alipour… - Biofactors, 2019 - Wiley Online Library
The present study aimed to investigate the role of microRNA‐146a and its adapter proteins
[interleukin‐1 receptor‐associated kinase 1 (IRAK1) and tumor necrosis factor (TNF) …

[HTML][HTML] Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice

MR Aslani, Z Jafari, R Rahbarghazi… - Iranian journal of …, 2022 - ncbi.nlm.nih.gov
Objective (s): Although various studies have revealed the beneficial effects of crocin (derived
from saffron), such as anti-inflammatory, anti-cancer, antioxidant, and immune modulator …

Modification of lung endoplasmic reticulum genes expression and NF-kB protein levels in obese ovalbumin-sensitized male and female rats

MR Aslani, H Ghobadi, H Panahpour, M Ahmadi… - Life sciences, 2020 - Elsevier
Aims Previous studies showed a close relationship between obesity and asthma. In this
study, we investigated the expression of endoplasmic reticulum (ER) stress genes in the …

Saffron (Crocus sativus) and its constituents in ovalbumin-induced asthma model: a preclinical systematic review and meta-analysis

H Ghobadi, F Aslani, MH Boskabady… - Frontiers in …, 2024 - frontiersin.org
Background Animal and human studies have demonstrated that the saffron and the active
components of saffron, including crocin, crocetin, and safranal, possess anti-inflammatory …

Emodin inhibits NF-κB signaling pathway to protect obese asthmatic rats from pathological damage via Visfatin

J Miao, X He, J Hu, W Cai - Tissue and Cell, 2022 - Elsevier
Purpose Emodin has a protective effect on asthma. Obesity is closely related to asthma. We
further explored the role of Emodin in obese asthmatic rats. Methods Ovalbumin (OVA) was …