MedalCare-XL: 16,900 healthy and pathological synthetic 12 lead ECGs from electrophysiological simulations

K Gillette, MAF Gsell, C Nagel, J Bender, B Winkler… - Scientific Data, 2023 - nature.com
Mechanistic cardiac electrophysiology models allow for personalized simulations of the
electrical activity in the heart and the ensuing electrocardiogram (ECG) on the body surface …

AugmentA: Patient-specific augmented atrial model generation tool

L Azzolin, M Eichenlaub, C Nagel, D Nairn… - … Medical Imaging and …, 2023 - Elsevier
Digital twins of patients' hearts are a promising tool to assess arrhythmia vulnerability and to
personalize therapy. However, the process of building personalized computational models …

Comparison of propagation models and forward calculation methods on cellular, tissue and organ scale atrial electrophysiology

C Nagel, CB Espinosa, K Gillette… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
Objective: The bidomain model and the finite element method are an established standard
to mathematically describe cardiac electrophysiology, but are both suboptimal choices for …

How synergy between mechanistic and statistical models is impacting research in atrial fibrillation

J Bai, Y Lu, H Wang, J Zhao - Frontiers in Physiology, 2022 - frontiersin.org
Atrial fibrillation (AF) with multiple complications, high morbidity and mortality, and low cure
rates, has become a global public health problem. Although significant progress has been …

Advancing clinical translation of cardiac biomechanics models: a comprehensive review, applications and future pathways

C Rodero, TMG Baptiste, RK Barrows, A Lewalle… - Frontiers in …, 2023 - frontiersin.org
Cardiac mechanics models are developed to represent a high level of detail, including
refined anatomies, accurate cell mechanics models, and platforms to link microscale …

[HTML][HTML] Defining myocardial fiber bundle architecture in atrial digital twins

R Piersanti, R Bradley, SY Ali, A Quarteroni… - ArXiv, 2024 - pmc.ncbi.nlm.nih.gov
A key component in developing atrial digital twins (ADT)-virtual representations of patients'
atria-is the accurate prescription of myocardial fibers which are essential for the tissue …

Medalcare-xl: 16,900 healthy and pathological 12 lead ecgs obtained through electrophysiological simulations

K Gillette, MAF Gsell, C Nagel, J Bender… - arXiv preprint arXiv …, 2022 - arxiv.org
Mechanistic cardiac electrophysiology models allow for personalized simulations of the
electrical activity in the heart and the ensuing electrocardiogram (ECG) on the body surface …

Modeling of cardiac fibers as oriented liquid crystals

NA Barnafi, A Osses - Computer Methods in Applied Mechanics and …, 2025 - Elsevier
In this work we propose a mathematical model that describes the orientation of ventricular
cardiac fibers. These fibers are commonly computed as the normalized gradient of certain …

Rule-based definition of muscle bundles in patient-specific models of the left atrium

S Rossi, L Abdala, A Woodward, JP Vavalle… - Frontiers in …, 2022 - frontiersin.org
Atrial fibrillation (AF) is the most common arrhythmia encountered clinically, and as the
population ages, its prevalence is increasing. Although the CHA2DS2− VASc score is the …

[HTML][HTML] Patient-specific left atrium contraction quantification associated with atrial fibrillation: A region-based approach

S Hussain, M Falanga, A Chiaravalloti, C Tomasi… - Computer Methods and …, 2024 - Elsevier
Background and objectives Atrial fibrillation (AF) is a widespread cardiac arrhythmia that
significantly impacts heart function. AF disrupts atrial mechanical contraction, leading to …