S100B is a calcium-binding protein mainly concentrated in astrocytes in the nervous system.
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …

Traumatic central nervous system (CNS) injury, which includes both traumatic brain injury
(TBI) and spinal cord injury (SCI), is associated with irreversible loss of neurological function …

Chronic pain is a maladaptive condition affecting 7%− 10% of the population worldwide and
can be accompanied by depression, anxiety, and insomnia. In particular, chronic pain is …

S100B is an astrocytic protein behaving at high concentration as a damage-associated
molecular pattern molecule. A direct correlation between the increased amount of S100B …

S100B is a calcium-binding protein mainly expressed by astrocytes, but also localized in
other definite neural and extra-neural cell types. While its presence in biological fluids is …

Background: Levodopa-induced dyskinesia (LID) is a common motor complication of
levodopa (L-DOPA) treatment for Parkinson's disease (PD). In recent years, the role of …

Regional neuropathic pain syndromes above, at, or below the site of spinal damage arise
after spinal cord injury (SCI) and are believed to entail distinct pathways; nevertheless, they …

Pathological neuropathic pain is a common complication following spinal cord injury. Due to
its high incidence, prolonged duration, tenacity, and limited therapeutic efficacy, it has …

Background This work aimed to analyze serum S100B levels and brain-derived
neurotrophic factor (BDNF) in patients with lumbar disc prolapse to test their predictive …

Background Pain in sickle cell disease (SCD) is severe and multifaceted resulting in
significant differences in its frequency and intensity among individuals. In this study, we …