[HTML][HTML] Exercise induces tissue-specific adaptations to enhance cardiometabolic health

SP Ashcroft, B Stocks, B Egan, JR Zierath - Cell metabolism, 2024 - cell.com
The risk associated with multiple cancers, cardiovascular disease, diabetes, and all-cause
mortality is decreased in individuals who meet the current recommendations for physical …

[PDF][PDF] Cardiovascular adaptations to exercise training

Y Hellsten, M Nyberg - Comprehensive physiology, 2011 - researchgate.net
Aerobic exercise training leads to cardiovascular changes that markedly increase aerobic
power and lead to improved endurance performance. The functionally most important …

Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy

FW Booth, MV Chakravarthy… - Journal of applied …, 2002 - journals.physiology.org
A hypothesis is presented based on a coalescence of anthropological estimations of Homo
sapiens' phenotypes in the Late Paleolithic era 10,000 years ago, with Darwinian natural …

Advances and challenges in skeletal muscle angiogenesis

IM Olfert, O Baum, Y Hellsten… - American journal of …, 2016 - journals.physiology.org
The role of capillaries is to serve as the interface for delivery of oxygen and removal of
metabolites to/from tissues. During the past decade there has been a proliferation of studies …

[HTML][HTML] TSC2 regulates VEGF through mTOR-dependent and-independent pathways

JB Brugarolas, F Vazquez, A Reddy, WR Sellers… - Cancer cell, 2003 - cell.com
Inactivation of the TSC2 tumor suppressor protein causes tuberous sclerosis complex (TSC),
a disease characterized by highly vascular tumors. TSC2 has multiple functions including …

Angiogenic growth factor expression in rat skeletal muscle in response to exercise training

PG Lloyd, BM Prior, HT Yang… - American Journal of …, 2003 - journals.physiology.org
Angiogenesis occurs in skeletal muscle in response to exercise training. To gain insight into
the regulation of this process, we evaluated the mRNA expression of factors implicated in …

[HTML][HTML] Exercise-induced skeletal muscle angiogenesis: impact of age, sex, angiocrines and cellular mediators

M Ross, CK Kargl, R Ferguson, TP Gavin… - European Journal of …, 2023 - Springer
Exercise-induced skeletal muscle angiogenesis is a well-known physiological adaptation
that occurs in humans in response to exercise training and can lead to endurance …

Influence of dietary nitrate on the physiological determinants of exercise performance: a critical review

AM Jones - Applied Physiology, Nutrition, and Metabolism, 2014 - cdnsciencepub.com
Dietary nitrate supplementation, usually in the form of beetroot juice, has been heralded as a
possible new ergogenic aid for sport and exercise performance. Early studies in …

Angiogenic growth factor response to acute systemic exercise in human skeletal muscle

TP Gavin, CB Robinson, RC Yeager… - Journal of applied …, 2004 - journals.physiology.org
We investigated whether acute systemic exercise increases vascular endothelial growth
factor (VEGF), VEGF receptor (KDR and Flt-1) mRNA, and VEGF protein in sedentary …

Exercise training improves aging-induced downregulation of VEGF angiogenic signaling cascade in hearts

M Iemitsu, S Maeda, S Jesmin… - American Journal of …, 2006 - journals.physiology.org
Exercise training improves aging-induced deterioration of angiogenesis in the heart.
However, the mechanisms underlying exercise-induced improvement of capillary density in …