Gut-derived low-grade endotoxaemia, atherothrombosis and cardiovascular disease

F Violi, V Cammisotto, S Bartimoccia… - Nature reviews …, 2023 - nature.com
Systemic inflammation has been suggested to have a pivotal role in atherothrombosis, but
the factors that trigger systemic inflammation have not been fully elucidated …

[HTML][HTML] Interrelation between ROS and Ca2+ in aging and age-related diseases

CT Madreiter-Sokolowski, C Thomas, M Ristow - Redox biology, 2020 - Elsevier
Abstract Calcium (Ca 2+) and reactive oxygen species (ROS) are versatile signaling
molecules coordinating physiological and pathophysiological processes. While channels …

Hypercoagulation and antithrombotic treatment in coronavirus 2019: a new challenge

F Violi, D Pastori, R Cangemi… - Thrombosis and …, 2020 - thieme-connect.com
The novel coronavirus 2019 (COVID-19) is clinically characterized by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for a high number …

[HTML][HTML] Biochemical basis and metabolic interplay of redox regulation

L Zhang, X Wang, R Cueto, C Effi, Y Zhang, H Tan… - Redox biology, 2019 - Elsevier
Accumulated evidence strongly indicates that oxidative stress, characterized by an
imbalance between reactive oxygen species (ROS) production and antioxidants in favor of …

[HTML][HTML] Nox2 activation in Covid-19

F Violi, A Oliva, R Cangemi, G Ceccarelli, P Pignatelli… - Redox Biology, 2020 - Elsevier
Nox2 is responsible for artery dysfunction via production of reactive oxidant species. RNA
viruses may activate Nox2, but it is unknown if this occurs in coronavirus 2019 (Covid-19) …

[PDF][PDF] Oxidative stress and cardiovascular disease: new insights

P Pignatelli, D Menichelli, D Pastori… - … Polska (Polish Heart …, 2018 - journals.viamedica.pl
Oxidative stress and cardiovascular disease: new insights Page 1 Address for correspondence:
Prof. Francesco Violi, I Clinica Medica, Viale del Policlinico 155, Roma, 00161, Italy, tel …

Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease

Q Yan, S Liu, Y Sun, C Chen, S Yang, M Lin… - Journal of Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …

Impact of miRNA in atherosclerosis

Y Lu, T Thavarajah, W Gu, J Cai… - … , thrombosis, and vascular …, 2018 - Am Heart Assoc
e160 Arterioscler Thromb Vasc Biol September 2018 were actively exported to the
cytoplasm with exportin-5 in a Ran-GTP–dependent manner. In the cytoplasm, the transition …

Thrombotic regulation from the endothelial cell perspectives

M Wang, H Hao, NJ Leeper, L Zhu - … , thrombosis, and vascular …, 2018 - Am Heart Assoc
Wang et al Endothelium in Thrombosis e91 endothelial TF may be enhanced in
pathophysiological conditions, 16, 17 and ECs were found to be able to secret …

Interventional study with vitamin E in cardiovascular disease and meta-analysis

F Violi, C Nocella, L Loffredo, R Carnevale… - Free Radical Biology …, 2022 - Elsevier
Cardiovascular disease (CVD) is one of the major causes of morbidity and mortality and
atherosclerosis is the common root to most of the CVD. Oxidative stress is one of the most …