The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the
systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve …

The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …

Transforming growth factor beta (TGF-β) is a pleiotropic cytokine present in vertebrate and
invertebrate organisms that functions in numerous physiological and pathological …

While popular belief harbors little doubt that perceived stress can cause hair loss and
premature graying, the scientific evidence for this is arguably much thinner. Here, we …

Uveitis, a group of conditions characterized by intraocular inflammation, is a major cause of
sight loss in the working population. Most uveitis seen in Western countries is noninfectious …

Macrophages are important in the activation of innate immune responses and in a tissue-
specific manner in the maintenance of organ homeostasis. Testicular macrophages (TM) …

Langerhans cells (LC) are a unique population of tissue-resident macrophages with
dendritic cell (DC) functionality that form a network of cells across the epidermis of the skin …

Fundamental cell signaling mechanisms that regulate dynamic remodeling of the
extracellular matrix (ECM) in mechanically loaded tissues are not yet clearly understood …

Glucocorticoids (GCs) are routinely administered systemically or injected into the eye when
treating numerous ocular diseases; however, their toxicity on the retinal microvasculature …

Abnormal corneal wound healing can compromise corneal transparency and lead to visual
impairment. Mineralocorticoid receptor antagonists (MRA) are promising candidates to …