[HTML][HTML] Single-cell transcriptional changes in neurodegenerative diseases

A Ahmadi, JD Gispert, A Navarro, N Vilor-Tejedor… - Neuroscience, 2021 - Elsevier
In recent decades, our understanding of the molecular changes involved in
neurodegenerative diseases has been transformed. Single-cell RNA sequencing and single …

The multitasker protein: a look at the multiple capabilities of NUMB

SM Ortega-Campos, JM García-Heredia - Cells, 2023 - mdpi.com
NUMB, a plasma membrane-associated protein originally described in Drosophila, is
involved in determining cell function and fate during early stages of development. It is …

SC2disease: a manually curated database of single-cell transcriptome for human diseases

T Zhao, S Lyu, G Lu, L Juan, X Zeng, Z Wei… - Nucleic Acids …, 2021 - academic.oup.com
Abstract SC2disease (http://easybioai. com/sc2disease/) is a manually curated database that
aims to provide a comprehensive and accurate resource of gene expression profiles in …

Single-cell analysis of the pan-cancer immune microenvironment and scTIME portal

F Hong, Q Meng, W Zhang, R Zheng, X Li… - Cancer Immunology …, 2021 - AACR
Single-cell sequencing opens a new era for the investigation of tumor immune
microenvironments (TIME). However, at single-cell resolution, a pan-cancer analysis that …

ABC portal: a single-cell database and web server for blood cells

X Gao, F Hong, Z Hu, Z Zhang, Y Lei, X Li… - Nucleic acids …, 2023 - academic.oup.com
Abstract ABC portal (http://abc. sklehabc. com) is a database and web portal containing 198
single-cell transcriptomic datasets of development, differentiation and disorder of …

Genome-wide association studies reveal neurological genes for dog herding, predation, temperament, and trainability traits

S Shan, F Xu, B Brenig - Frontiers in Veterinary Science, 2021 - frontiersin.org
Genome-wide association study (GWAS) using dog breed standard values as phenotypic
measurements is an efficient way to identify genes associated with morphological and …

TMExplorer: a tumour microenvironment single-cell RNAseq database and search tool

E Christensen, A Naidas, D Chen, M Husic… - Plos one, 2022 - journals.plos.org
Motivation The tumour microenvironment (TME) contains various cells including stromal
fibroblasts, immune and malignant cells, and its composition can be elucidated using single …

A statistical approach for systematic identification of transition cells from scRNA-seq data

Y Wang, M Dede, V Mohanty, J Dou, Z Li, K Chen - Cell Reports Methods, 2024 - cell.com
Decoding cellular state transitions is crucial for understanding complex biological processes
in development and disease. While recent advancements in single-cell RNA sequencing …

[HTML][HTML] NTCdb: Single-cell transcriptome database of human inflammatory-associated diseases

C Wang, T Huyan, W Guo, Q Shu, Q Li, J Shi - Computational and Structural …, 2024 - Elsevier
With both the advancement of technology and the decline in costs, single-cell
transcriptomics sequencing has become widespread in the biomedical area in recent years …

OrganogenesisDB: A Comprehensive Database Exploring the Cell‐Type Identities and Gene Expression Dynamics during Organogenesis

X Zhang, J Ma, H Li, Y Zhai, F He, X Wang… - Small Methods, 2024 - Wiley Online Library
Organogenesis, the phase of embryonic development that starts at the end of gastrulation
and continues until birth is the critical process for understanding cellular differentiation and …