Carbohydrate binding modules: diversity of domain architecture in amylases and cellulases from filamentous microorganisms

A Sidar, ED Albuquerque, GP Voshol… - … in Bioengineering and …, 2020 - frontiersin.org
Enzymatic degradation of abundant renewable polysaccharides such as cellulose and
starch is a field that has the attention of both the industrial and scientific community. Most of …

The cellulosomes: multienzyme machines for degradation of plant cell wall polysaccharides

EA Bayer, JP Belaich, Y Shoham… - Annu. Rev. Microbiol …, 2004 - annualreviews.org
▪ Abstract The discrete multicomponent, multienzyme cellulosome complex of anaerobic
cellulolytic bacteria provides enhanced synergistic activity among the different resident …

Integrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes

A Heintz-Buschart, P May, CC Laczny, LA Lebrun… - Nature …, 2016 - nature.com
The gastrointestinal microbiome is a complex ecosystem with functions that shape human
health. Studying the relationship between taxonomic alterations and functional …

Cellulase, clostridia, and ethanol

AL Demain, M Newcomb, JHD Wu - Microbiology and molecular …, 2005 - Am Soc Microbiol
Biomass conversion to ethanol as a liquid fuel by the thermophilic and anaerobic clostridia
offers a potential partial solution to the problem of the world's dependence on petroleum for …

The cellulosome and cellulose degradation by anaerobic bacteria

W Schwarz - Applied microbiology and biotechnology, 2001 - Springer
Despite its simple chemical composition, cellulose exists in a number of crystalline and
amorphous topologies. Its insolubility and heterogeneity makes native cellulose a …

Clostridium cellulolyticum: model organism of mesophilic cellulolytic clostridia

M Desvaux - FEMS microbiology reviews, 2005 - academic.oup.com
Clostridium cellulolyticum ATCC 35319 is a non-ruminal mesophilic cellulolytic bacterium
originally isolated from decayed grass. As with most truly cellulolytic clostridia, C …

Thermophiles and carbohydrate-active enzymes (CAZymes) in biofilm microbial consortia that decompose lignocellulosic plant litters at high temperatures

KJ Liew, CH Liang, YT Lau, AS Yaakop, KG Chan… - Scientific Reports, 2022 - nature.com
The SKY hot spring is a unique site filled with a thick layer of plant litter. With the
advancement of next-generation sequencing, it is now possible to mine many new …

Cellulosomes: microbial nanomachines that display plasticity in quaternary structure

HJ Gilbert - Molecular microbiology, 2007 - Wiley Online Library
The assembly of proteins that display complementary activities into supramolecular intra‐
and extracellular complexes is central to cellular function. One such nanomachine of …

A synthetic biology approach for evaluating the functional contribution of designer cellulosome components to deconstruction of cellulosic substrates

Y Vazana, Y Barak, T Unger, Y Peleg… - Biotechnology for …, 2013 - Springer
Background Select cellulolytic bacteria produce multi-enzymatic cellulosome complexes that
bind to the plant cell wall and catalyze its efficient degradation. The multi-modular …

Identification of homology in protein structure classification

S Dietmann, L Holm - nature structural biology, 2001 - nature.com
Structural biology and structural genomics are expected to produce many three-dimensional
protein structures in the near future. Each new structure raises questions about its function …