Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in
regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited …

Follicle-stimulating hormone signaling is essential for the initiation and early stages of
spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli …

Antioxidant actions of melatonin and its impact on testicular function and fertility have
already been described. Considering that Sertoli cells contribute to provide structural …

Sertoli cells play a central role in spermatogenesis. They maintain the blood-testis barrier,
an essential feature of seminiferous tubules which creates the proper environment for the …

Dysfunction of spermatogenesis is a major complication of diabetes mellitus (DM). This
study characterized the protective effects of Dendrobium nobile-derived polysaccharides …

Lead (Pb) exists widely in soil and seriously threatens agricultural soil and food crops. Pb
can cause serious damage to organs. In this study, the animal model of Pb-induced rat …

Scope Obesity is a global threat for male infertility, which can cause spermatogenic
dysfunction. However, there are no available drugs for the treatment of obesity‐induced …

Backgrounds In the testis, spermatocytes and spermatids rely on lactate produced by Sertoli
cells (SCs) as energy source. Transforming growth factor‐beta 3 (TGF‐β3) is one of the …

Sertoli cells (SCs) possess the unparalleled ability to provide the germ line with growth
factors and nutrients. Although SCs can oxidize amino acids, eg, glutamine, they mostly …

Fumonisin B1 (FB1), a mycotoxin produced by Fusarium species, is prevalent in crops and
animal feed, posing significant health risks to livestock and humans. FB1 induces oxidative …