Sympathetic transduction in humans: recent advances and methodological considerations

BE Young, JL Greaney, DM Keller… - American Journal of …, 2021 - journals.physiology.org
Ever since their origin more than one half-century ago, microneurographic recordings of
sympathetic nerve activity have significantly advanced our understanding of the generation …

A sympathetic view of blood pressure control at high altitude: new insights from microneurographic studies

LL Simpson, CD Steinback… - Experimental …, 2021 - Wiley Online Library
New Findings What is the topic of the review? Sympathoexcitation and sympathetic control
of blood pressure at high altitude. What advances does it highlight? Sustained …

Sympathetic transduction of blood pressure during graded lower body negative pressure in young healthy adults

M Nardone, C Katerberg, AL Teixeira… - American Journal …, 2022 - journals.physiology.org
Sympathetic transduction of blood pressure (BP) is correlated negatively with resting muscle
sympathetic nerve activity (MSNA) in cross-sectional data, but the acute effects of increasing …

Signal-averaged resting sympathetic transduction of blood pressure: is it time to account for prevailing muscle sympathetic burst frequency?

M Nardone, AV Incognito, MM Kathia… - American Journal …, 2021 - journals.physiology.org
Calculating the blood pressure (BP) response to a burst of muscle sympathetic nerve activity
(MSNA), termed sympathetic transduction, may be influenced by an individual's resting burst …

Mechanisms underpinning sympathoexcitation in hypoxia

LL Simpson, M Stembridge… - The Journal of …, 2024 - Wiley Online Library
Sympathoexcitation is a hallmark of hypoxic exposure, occurring acutely, as well as
persisting in acclimatised lowland populations and with generational exposure in highland …

An open-source program to analyze spontaneous sympathetic neurohemodynamic transduction

MW O'Brien, JL Petterson… - Journal of …, 2021 - journals.physiology.org
The sympathetic nervous system is important for the beat-by-beat regulation of arterial blood
pressure and the control of blood flow to various organs. Microneurographic recordings of …

Acute hypoxia elicits lasting reductions in the sympathetic action potential transduction of arterial blood pressure in males

BM Shafer, M Nardone, AV Incognito… - The Journal of …, 2023 - Wiley Online Library
Post‐hypoxia sympathoexcitation does not elicit corresponding changes in vascular tone,
suggesting diminished sympathetic signalling. Blunted sympathetic transduction following …

Blunted sympathetic neurovascular transduction is associated to the severity of obstructive sleep apnea

AR Steele, LF Berthelsen, GM Fraser… - Clinical Autonomic …, 2021 - Springer
Purpose Obstructive sleep apnea (OSA) is a common disorder (~ 4%) that augments
sympathetic nerve activity (SNA) and elevates blood pressure. The relationship between …

Aerobic fitness is inversely associated with neurohemodynamic transduction and blood pressure variability in older adults

MW O'Brien, DJ Ramsay, CD O'Neill, JL Petterson… - GeroScience, 2021 - Springer
Higher aerobic fitness is independently associated with better cardiovascular health in older
adults. The transduction of muscle sympathetic nerve activity (MSNA) into mean arterial …

Concomitantly higher resting arterial blood pressure and transduction of sympathetic neural activity in human obesity without hypertension

SW Holwerda, ME Gangwish, RE Luehrs… - Journal of …, 2023 - journals.lww.com
Objective: Central (abdominal) obesity is associated with elevated adrenergic activity and
arterial blood pressure (BP). Therefore, we tested the hypothesis that transduction of …