Intrinsically disordered proteins play diverse roles in cell signaling
Signaling pathways allow cells to detect and respond to a wide variety of chemical (eg Ca2+
or chemokine proteins) and physical stimuli (eg, sheer stress, light). Together, these …
or chemokine proteins) and physical stimuli (eg, sheer stress, light). Together, these …
[HTML][HTML] Nuclear localization and actions of the insulin-like growth factor 1 (IGF-1) system components: Transcriptional regulation and DNA damage response
E Poreba, J Durzynska - Mutation Research/Reviews in Mutation Research, 2020 - Elsevier
Insulin-like growth factor (IGF) system stimulates growth, proliferation, and regulates
differentiation of cells in a tissue-specific manner. It is composed of two insulin-like growth …
differentiation of cells in a tissue-specific manner. It is composed of two insulin-like growth …
Brain wave classification using long short-term memory network based OPTICAL predictor
Brain-computer interface (BCI) systems having the ability to classify brain waves with greater
accuracy are highly desirable. To this end, a number of techniques have been proposed …
accuracy are highly desirable. To this end, a number of techniques have been proposed …
An improved discriminative filter bank selection approach for motor imagery EEG signal classification using mutual information
Background Common spatial pattern (CSP) has been an effective technique for feature
extraction in electroencephalography (EEG) based brain computer interfaces (BCIs) …
extraction in electroencephalography (EEG) based brain computer interfaces (BCIs) …
[HTML][HTML] Computational prediction of MoRFs, short disorder-to-order transitioning protein binding regions
Molecular recognition features (MoRFs) are short protein-binding regions that undergo
disorder-to-order transitions (induced folding) upon binding protein partners. These regions …
disorder-to-order transitions (induced folding) upon binding protein partners. These regions …
Computational prediction of disordered binding regions
One of the key features of intrinsically disordered regions (IDRs) is their ability to interact
with a broad range of partner molecules. Multiple types of interacting IDRs were identified …
with a broad range of partner molecules. Multiple types of interacting IDRs were identified …
OPAL: prediction of MoRF regions in intrinsically disordered protein sequences
Motivation Intrinsically disordered proteins lack stable 3-dimensional structure and play a
crucial role in performing various biological functions. Key to their biological function are the …
crucial role in performing various biological functions. Key to their biological function are the …
Protein function analysis through machine learning
Machine learning (ML) has been an important arsenal in computational biology used to
elucidate protein function for decades. With the recent burgeoning of novel ML methods and …
elucidate protein function for decades. With the recent burgeoning of novel ML methods and …
Protein secondary structure prediction: a review of progress and directions
T Smolarczyk, I Roterman-Konieczna… - Current …, 2020 - ingentaconnect.com
Background: Over the last few decades, a search for the theory of protein folding has grown
into a full-fledged research field at the intersection of biology, chemistry and informatics …
into a full-fledged research field at the intersection of biology, chemistry and informatics …
APOD: accurate sequence-based predictor of disordered flexible linkers
Abstract Motivation Disordered flexible linkers (DFLs) are abundant and functionally
important intrinsically disordered regions that connect protein domains and structural …
important intrinsically disordered regions that connect protein domains and structural …