Natural biomaterials for cardiac tissue engineering: a highly biocompatible solution
QA Majid, ATR Fricker, DA Gregory… - Frontiers in …, 2020 - frontiersin.org
Cardiovascular diseases (CVD) constitute a major fraction of the current major global
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …
Eutectic mixtures as an approach to enhance solubility, dissolution rate and oral bioavailability of poorly water-soluble drugs
Eutectic mixtures have been known for a long time in the pharmaceutical field. However, its
potential as a system to improve the solubility and dissolution of poorly water-soluble drugs …
potential as a system to improve the solubility and dissolution of poorly water-soluble drugs …
Soluplus-mediated diosgenin amorphous solid dispersion with high solubility and high stability: development, characterization and oral bioavailability
P Liu, J Zhou, J Chang, X Liu, H Xue… - Drug design …, 2020 - Taylor & Francis
Background and Purpose The traditional Chinese medicine, diosgenin (Dio), has attracted
increasing attention because it possesses various therapeutic effects, including anti-tumor …
increasing attention because it possesses various therapeutic effects, including anti-tumor …
Cellulose derivatives as effective recrystallization inhibitor for ternary ritonavir solid dispersions: In vitro-in vivo evaluation
Q Guan, Q Ma, Y Zhao, X Jiang, H Zhang, M Liu… - Carbohydrate …, 2021 - Elsevier
Amorphous solid dispersions (ASDs) are regarded as one of the most promising techniques
for poorly-soluble active pharmaceutical ingredients (API). However, the thermodynamic …
for poorly-soluble active pharmaceutical ingredients (API). However, the thermodynamic …
Tailoring Chlorthalidone Aqueous Solubility by Cocrystallization: Stability and Dissolution Behavior of a Novel Chlorthalidone-Caffeine Cocrystal
C Rodríguez-Ruiz, P Montes-Tolentino… - Pharmaceutics, 2022 - mdpi.com
A cocrystal of the antihypertensive drug chlorthalidone (CTD) with caffeine (CAF) was
obtained (CTD-CAF) by the slurry method, for which a 2: 1 stoichiometric ratio was found by …
obtained (CTD-CAF) by the slurry method, for which a 2: 1 stoichiometric ratio was found by …
Effects of hypromellose acetate succinate on recrystallization inhibition, miscibility, and dissolution enhancement of baloxavir marboxil solid dispersions
L Wang, H Wu, Z Wang, Z Ding, Y Zhao, S Li… - International Journal of …, 2024 - Elsevier
Solid dispersions (SDs) have emerged as a promising strategy to enhance the solubility and
bioavailability of poorly soluble active pharmaceutical ingredients. However, SDs tend to …
bioavailability of poorly soluble active pharmaceutical ingredients. However, SDs tend to …
Formulation and In Vitro Characterization of a Vacuum-Dried Drug–Polymer Thin Film for Intranasal Application
D Inoue, A Yamashita, H To - Polymers, 2022 - mdpi.com
Intranasal drug applications show significant therapeutic potential for diverse
pharmaceutical modalities. Because the formulation applied to the nasal cavity is …
pharmaceutical modalities. Because the formulation applied to the nasal cavity is …
Sodium alginate based fast swelling nanogels for solubility enhancement of chlorthalidone; synthesis, characterization and biosafety evaluation
SF Badshah, O Abdullah, KU Khan… - Biomedical …, 2024 - iopscience.iop.org
Purpose of the study was to enhance the solubility of chlorthalidone, poorly soluble diuretic
that has been the used for lowering high blood pressure for the past half-century. Solubility …
that has been the used for lowering high blood pressure for the past half-century. Solubility …
The role of glycyrrhizic acid in colloidal phenomena of supersaturation drug delivery systems containing the antifungal drug griseofulvin
The ability of carriers to inhibit precipitation may determine supersaturating drug delivery
systems capability of improving poorly soluble drugs bioavailability. It was hypothesized that …
systems capability of improving poorly soluble drugs bioavailability. It was hypothesized that …
Polymer/lipid interplay in altering in vitro supersaturation and plasma concentration of a model poorly soluble drug
R Peng, J Huang, L He, L Zhao, C Wang, W Wei… - European Journal of …, 2020 - Elsevier
Supersaturation drug delivery system (SDDS) based on amorphous solid dispersion (ASD)
is a widely used strategy to improve oral absorption of poorly water-soluble drugs by …
is a widely used strategy to improve oral absorption of poorly water-soluble drugs by …