Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

Interdisciplinary‐inspired smart antibacterial materials and their biomedical applications

Y Wu, P Liu, B Mehrjou, PK Chu - Advanced Materials, 2024 - Wiley Online Library
The discovery of antibiotics has saved millions of lives, but the emergence of antibiotic‐
resistant bacteria has become another problem in modern medicine. To avoid or reduce the …

Antimicrobial polymeric nanoparticles

SJ Lam, EHH Wong, C Boyer, GG Qiao - Progress in polymer science, 2018 - Elsevier
Currently, infections caused by multidrug-resistant bacteria have reached critical levels.
Thus, various approaches are being explored for the development of new and effective …

Biomimetic antimicrobial polymers: Recent advances in molecular design

C Ergene, K Yasuhara, EF Palermo - Polymer Chemistry, 2018 - pubs.rsc.org
The increasing prevalence of antibiotic-resistant bacterial infections, coupled with the
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …

Controlling macromolecular structures towards effective antimicrobial polymers

MS Ganewatta, C Tang - Polymer, 2015 - Elsevier
Drug resistance of pathogenic bacteria is a major global problem leading humanity towards
a pre-antibiotic era. Decline in the discovery of novel antibiotics and the lack of a resilient …

Synthetic random copolymers as a molecular platform to mimic host-defense antimicrobial peptides

H Takahashi, GA Caputo, S Vemparala… - Bioconjugate …, 2017 - ACS Publications
Synthetic polymers have been used as a molecular platform to develop host-defense
antimicrobial peptide (AMP) mimetics which are effective in killing drug-resistant bacteria. In …

Decoupling the functional roles of cationic and hydrophobic groups in the antimicrobial and hemolytic activities of methacrylate random copolymers

H Mortazavian, LL Foster, R Bhat, S Patel… - …, 2018 - ACS Publications
In this study, we report the antimicrobial and hemolytic activities of ternary statistical
methacrylate copolymers consisting of cationic ammonium (amino-ethyl methacrylate …

Biocidal polymers: a mechanistic overview

A Chen, H Peng, I Blakey, AK Whittaker - Polymer Reviews, 2017 - Taylor & Francis
Bacterial fouling on surfaces is considered a major problem in modern society. Conventional
methods to prevent biofilm formation often have little effect and may induce further …

Constructing antibacterial polymer nanocapsules based on pyridine quaternary ammonium salt

M Zeng, J Xu, Q Luo, C Hou, S Qiao, S Fu, X Fan… - Materials Science and …, 2020 - Elsevier
Excessive use of antibiotics accelerates the development and spread of drug-resistant
strains, which is a huge challenge for the field of medical health worldwide. Quaternary …

Isosteric substitution in cationic-amphiphilic polymers reveals an important role for hydrogen bonding in bacterial membrane interactions

D Uppu, MM Konai, U Baul, P Singh, TK Siersma… - Chemical …, 2016 - pubs.rsc.org
Biomimetic antibacterial polymers, the functional mimics of antimicrobial peptides (AMPs),
targeting the bacterial cell membrane have been developed to combat the problem of …