Infectious and Inflammatory Microenvironment Self‐Adaptive Artificial Peroxisomes with Synergetic Co‐Ru Pair Centers for Programmed Diabetic Ulcer Therapy
Y Gao, Y Deng, W Geng, S Xiao, T Wang… - Advanced …, 2024 - Wiley Online Library
Complex microenvironments with bacterial infection, persistent inflammation, and impaired
angiogenesis are the major challenges in chronic refractory diabetic ulcers. To address this …
angiogenesis are the major challenges in chronic refractory diabetic ulcers. To address this …
Inhibition of MurA Enzyme from Escherichia coli by Flavonoids and Their Synthetic Analogues
R Frlan, M Hrast, S Gobec - ACS omega, 2023 - ACS Publications
MurA catalyzes the first step of peptidoglycan (PG) biosynthesis and is a validated target for
the development of new antimicrobial agents. In this study, a library of 49 plant flavonoids …
the development of new antimicrobial agents. In this study, a library of 49 plant flavonoids …
Genetic interaction mapping reveals functional relationships between peptidoglycan endopeptidases and carboxypeptidases
M Alvarado Obando, D Rey-Varela, F Cava… - Plos Genetics, 2024 - journals.plos.org
Peptidoglycan (PG) is the main component of the bacterial cell wall; it maintains cell shape
while protecting the cell from internal osmotic pressure and external environmental …
while protecting the cell from internal osmotic pressure and external environmental …
Role of UDP‐N‐acetylmuramic acid in the regulation of MurA activity revealed by molecular dynamics simulations
MVD de Oliveira, KS da Costa, JRA Silva… - Protein …, 2024 - Wiley Online Library
The peptidoglycan biosynthesis pathway plays a vital role in bacterial cells, and facilitates
peptidoglycan layer formation, a fundamental structural component of the bacterial cell wall …
peptidoglycan layer formation, a fundamental structural component of the bacterial cell wall …
Synthesis and inhibitory activity against MurA and MurZ enzymes of 4 H-pyrano [2, 3-d] pyrimidine–1 H-1, 2, 3-triazole hybrid compounds having piperidine and …
DT Nguyen, SH Do, NT Vu, TK Van Hoang… - New Journal of …, 2023 - pubs.rsc.org
A series of D-glucose-conjugated 4H-pyrano [2, 3-d] pyrimidine–1H-1, 2, 3-triazole hybrid
compounds 12a–g and 13a–g having piperidine and morpholine rings were synthesized by …
compounds 12a–g and 13a–g having piperidine and morpholine rings were synthesized by …
Antibacterial Potential of Ximenia americana L. Olacaceae: Molecular Docking, Molecular Dynamics, and ADMET Prediction
MM Dahiru, AM Abaka, I Ya'u - Journal of Pharmacy, 2024 - journals.iium.edu.my
Introduction: The devastating effect of persistent and recurrent bacterial infections coupled
with antibiotic resistance is a driving force for prospects into alternative antibacterial …
with antibiotic resistance is a driving force for prospects into alternative antibacterial …
Molecular modelling and site-directed mutagenesis provide insight into saccharide pyruvylation by the Paenibacillus alvei CsaB enzyme
C Stefanović, FF Hager-Mair, E Breslmayr… - Scientific Reports, 2023 - nature.com
Pyruvylation is a biologically versatile but mechanistically unexplored saccharide
modification. 4, 6-Ketal pyruvylated N-acetylmannosamine within bacterial secondary cell …
modification. 4, 6-Ketal pyruvylated N-acetylmannosamine within bacterial secondary cell …
Flavoenzymes in Microbial Systems: Analysis of Structure-Function Relationships
MI Minjarez Saenz, MM Medina Trullenque… - zaguan.unizar.es
Esta Tesis Doctoral se planteó con objeto de mejorar nuestra comprensión de los
mecanismos de acción específicos de especie en sistemas dependientes de flavoenzimas …
mecanismos de acción específicos de especie en sistemas dependientes de flavoenzimas …
[PDF][PDF] Flavoenzymes in Microbial Systems: Analysis of Structure-Function Relationships
MM Medina Trullenque, MM Martínez Júlvez - zaguan.unizar.es
Structure-Function Relationships” ha sido realizada por la licenciada MARTHA MINJÁREZ
SÁENZ en el Departamento de Bioquímica y Biología Molecular y Celular (Facultad de …
SÁENZ en el Departamento de Bioquímica y Biología Molecular y Celular (Facultad de …
[HTML][HTML] Novel role for peptidoglycan carboxypeptidases in maintaining the balance between bacterial cell wall synthesis and degradation
MA Obando, T Dörr - bioRxiv, 2023 - ncbi.nlm.nih.gov
Peptidoglycan (PG) is the main component of the bacterial cell wall; it maintains cell shape
while protecting the cell from internal osmotic pressure and external environmental …
while protecting the cell from internal osmotic pressure and external environmental …