Cystic fibrosis is a frequent autosomal recessive disorder that is caused by the
malfunctioning of a small chloride channel, the cystic fibrosis transmembrane conductance …

Application of atomic force microscopy (AFM) on isolated plasma membranes is a valuable
method to study membrane proteins down to single-molecule level in their native …

Previously, the pleiotropic “master kinase” casein kinase 2 (CK2) was shown to interact with
CFTR, the protein responsible for cystic fibrosis (CF). Moreover, CK2 inhibition abolished …

The cystic fibrosis transmembrane conductance regulator (CFTR) channel is regulated by
cAMP-dependent vesicle traffic and exocytosis to the apical membrane in some cell types …

Cystic fibrosis (CF) is the most common life-shortening autosomal recessively inherited
disorder among Caucasians (1 in 2500), but is found in all racial and ethnic groups (Welsh …

Although phosphatidylinositol 3-kinase (PI3K) is essential for several cellular signal
transductions, its role in the regulation of cystic fibrosis transmembrane conductance …

The adaptation of the capacity of the intestinal peptide transporter PEPT1 to varying
substrate concentrations may be important with respect to its role in providing bulk quantities …

Previous studies have implicated annexins in regulating ion channels and in particular
annexin A5 (AnxA5) in the traffic of the cystic fibrosis transmembrane conductance regulator …

Previous studies from this laboratory demonstrated a role for protein kinase C (PKC) ε in the
regulation of cAMP-dependent cystic fibrosis transmembrane regulator (CFTR) Cl channel …

The presence of sugar in the gut causes induction of SGLT1, the sodium/glucose
cotransporter in intestinal epithelial cells (enterocytes), and this is accompanied by …