Antimicrobial peptides towards clinical application: Delivery and formulation

C Wang, T Hong, P Cui, J Wang, J Xia - Advanced drug delivery reviews, 2021 - Elsevier
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat
the multidrug resistant microbes. There are however technical hurdles towards the clinical …

Ferrocene-based drugs, delivery nanomaterials and fenton mechanism: state of the art, recent developments and prospects

C Ornelas, D Astruc - Pharmaceutics, 2023 - mdpi.com
Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …

Therapeutic potential of antimicrobial peptides against pathogenic protozoa

CL Hagemann, AJ Macedo, T Tasca - Parasitology Research, 2024 - Springer
Protozoal infections cause significant morbidity and mortality in humans and animals. The
use of several antiprotozoal drugs is associated with serious adverse effects and resistance …

Electrochemical detection of waterborne bacteria using bi-functional magnetic nanoparticle conjugates

D Gunasekaran, Y Gerchman, S Vernick - Biosensors, 2022 - mdpi.com
Detection of microbial contamination in water is imperative to ensure water quality. We have
developed an electrochemical method for the detection of E. coli using bi-functional …

[HTML][HTML] MM-GBSA and QM/MM simulation-based in silico approaches for the inhibition of Acinetobacter baumannii class D OXA-24 β-lactamase using antimicrobial …

M Mandal, S Mandal - Chemical Physics Impact, 2024 - Elsevier
The antimicrobial peptides (AMPs) have been regarded as the next generation antibiotics.
This study aimed to explore the AMP inhibitors of β-lactamase enzyme employing …

Development of New Leishmanicidal Compounds via Bioconjugation of Antimicrobial Peptides and Antileishmanial Guanidines

NCS Costa, LR Dos Anjos, JVM de Souza… - ACS …, 2023 - ACS Publications
Leishmaniasis refers to a collection of diseases caused by protozoa from the Leishmania
genus. These diseases, along with other parasitic afflictions, pose a significant public health …

Study of the physicochemical and biological properties of the lipid complex of marine microalgae isolated from the coastal areas of the eastern water area of the Baltic …

V Dolganyuk, A Andreeva, S Sukhikh, E Kashirskikh… - Molecules, 2022 - mdpi.com
The Baltic Sea algae species composition includes marine euryhaline, freshwater
euryhaline, and true brackish water forms. This study aimed to isolate a lipid–pigment …

Role of organometallic complexes in targeted therapies of different diseases: Infectious diseases, Cancer and Neurodegenerative Diseases

V Nitin, T Anand, CK Singh, KK Sodhi - Journal of Organometallic …, 2024 - Elsevier
Organometallic complexes have garnered attention in the design of metal
chemotherapeutics in recent years because of their exceptional stability and distinct …

Systematic review of antiprotozoal potential of antimicrobial peptides

FA Santos, GS Cruz, FA Vieira, BRS Queiroz… - Acta Tropica, 2022 - Elsevier
Protozoa is a group of microorganisms that cause neglected tropical diseases, such as
malaria, Chagas disease, and Leishmaniasis. Due to the growing demand for new …

Understanding the mechanism of action of peptide (p-BthTX-I) 2 derived from C-terminal region of phospholipase A2 (PLA2)-like bothropstoxin-I on Gram-positive and …

NA Santos-Filho, LM de Freitas, CT Dos Santos… - Toxicon, 2021 - Elsevier
Based on the antimicrobial activity of bothropstoxin-I (BthTX-I) and on the premise that a C-
terminal peptide of Lys49 myotoxin can reproduce the antimicrobial activity of the parent …