Mucosal applications of poloxamer 407-based hydrogels: An overview

E Giuliano, D Paolino, M Fresta, D Cosco - Pharmaceutics, 2018 - mdpi.com
Poloxamer 407, also known by the trademark Pluronic® F127, is a water-soluble, non-ionic
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …

Local drug delivery systems in the management of periodontitis: A scientific review

HR Rajeshwari, D Dhamecha, S Jagwani… - Journal of Controlled …, 2019 - Elsevier
Periodontitis (PD) is a microbial disease of tooth supporting tissues that results in
progressive destruction of surrounding soft and hard tissues with eventual tooth mobility and …

Interactions with microbial proteins driving the antibacterial activity of flavonoids

G Donadio, F Mensitieri, V Santoro, V Parisi… - Pharmaceutics, 2021 - mdpi.com
Flavonoids are among the most abundant natural bioactive compounds produced by plants.
Many different activities have been reported for these secondary metabolites against …

Phytosynthesis of silver nanoparticles: characterization, biocompatibility studies, and anticancer activity

K Jadhav, S Deore, D Dhamecha, R Hr… - ACS Biomaterials …, 2018 - ACS Publications
Silver nanoparticles (SNPs), owing to their wide range of biomedical applications, have
recently attracted remarkable interest for use in cancer nanomedicine. The present research …

An overview on thermosensitive oral gel based on poloxamer 407

Y Chen, JH Lee, M Meng, N Cui, CY Dai, Q Jia, ES Lee… - Materials, 2021 - mdpi.com
In this review, we describe the application of thermosensitive hydrogels composed of
poloxamer in medicine, especially for oral cavities. Thermosensitive hydrogels remain fluid …

Pharmacokinetic and pharmacodynamic evaluation of resveratrol loaded cationic liposomes for targeting hepatocellular carcinoma

S Jagwani, S Jalalpure, D Dhamecha… - ACS Biomaterials …, 2020 - ACS Publications
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death
worldwide. The destructive nature of the disease makes it difficult for clinicians to manage …

[HTML][HTML] Antimicrobial and anti-inflammatory thermo-reversible hydrogel for periodontal delivery

B Wang, HE Booij-Vrieling, EM Bronkhorst, J Shao… - Acta biomaterialia, 2020 - Elsevier
In periodontal treatment, topical adjunctive therapy with antimicrobials or anti-inflammatory
agents is frequently applied. However, currently available drug carrier biomaterials often …

Lipopeptide liposomes-loaded hydrogel for multistage transdermal chemotherapy of melanoma

Y Ni, W Zhao, W Cheng, C Deng, Z Ying, L Li… - Journal of Controlled …, 2022 - Elsevier
Transdermal administration of chemotherapeutics into tumor tissues may be an effective
treatment to reduce toxic side effects and improve patient compliance for melanoma. Herein …

Local drug delivery systems for inflammatory diseases: Status quo, challenges, and opportunities

YC Chen, SF Gad, D Chobisa, Y Li, Y Yeo - Journal of Controlled Release, 2021 - Elsevier
Inflammation that is not resolved in due course becomes a chronic disease. The treatment of
chronic inflammatory diseases involves a long-term use of anti-inflammatory drugs such as …

Thermosensitive hydrogels loaded with resveratrol nanoemulsion: Formulation optimization by central composite design and evaluation in MCF-7 human breast …

S Kotta, HM Aldawsari, SM Badr-Eldin, AB Nair… - Gels, 2022 - mdpi.com
The second most common cause of mortality among women is breast cancer. A variety of
natural compounds have been demonstrated to be beneficial in the management of various …