Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …

Lysosome-mediated autophagy and caspase-dependent apoptosis are dynamic processes
that maintain cellular homeostasis, ensuring cell health and functionality. The intricate …

Autophagy and apoptosis represent two fundamental pathophysiological mechanisms of cell
fate regulation. However, the signaling pathways of these processes are significantly …

Endoplasmic reticulum (ER)-mitochondria contact sites are crucial to allow Ca 2+ flux
between them and a plethora of proteins participate in tethering both organelles together …

Transarterial chemoembolization (TACE) is commonly used for treating advanced
hepatocellular carcinoma (HCC). However, the instability of lipiodol-drug emulsion and the …

It is well established that ryanodine receptors (RyanRs) are overactive in Alzheimer's
disease (AD), and it has been suggested that inhibition of RyanR is potentially beneficial for …

Platinum (IV) prodrugs c, c, t-[PtCl 2 (NH 3) 2 (OH)(amlexanox)](MAP) and c, c, t-[PtCl 2 (NH
3) 2 (amlexanox) 2](DAP) were synthesized by reacting amlexanox with oxoplatin and …

Long-term ingestion of arsenicals, a heterogeneous group of toxic compounds, has been
associated with a wide spectrum of human pathologies, which include various malignancies …

Breast cancer is the most prevalent malignancy among women. Doxorubicin (Dox)
resistance was one of the major obstacles to improving the clinical outcome of breast cancer …

Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …