Gene set analysis: challenges, opportunities, and future research
Gene set analysis methods are widely used to provide insight into high-throughput gene
expression data. There are many gene set analysis methods available. These methods rely …
expression data. There are many gene set analysis methods available. These methods rely …
Pharmacogenomics for the efficacy and side effects of antihistamines
L Li, R Liu, C Peng, X Chen, J Li - Experimental Dermatology, 2022 - Wiley Online Library
Antihistamines, especially H1 antihistamines, are widely used in the treatment of allergic
diseases such as urticaria and allergic rhinitis, mainly for reversing elevated histamine and …
diseases such as urticaria and allergic rhinitis, mainly for reversing elevated histamine and …
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins
AD Rouillard, GW Gundersen, NF Fernandez… - Database, 2016 - academic.oup.com
Genomics, epigenomics, transcriptomics, proteomics and metabolomics efforts rapidly
generate a plethora of data on the activity and levels of biomolecules within mammalian …
generate a plethora of data on the activity and levels of biomolecules within mammalian …
iRegulon: from a gene list to a gene regulatory network using large motif and track collections
R Janky, A Verfaillie, H Imrichová… - PLoS computational …, 2014 - journals.plos.org
Identifying master regulators of biological processes and mapping their downstream gene
networks are key challenges in systems biology. We developed a computational method …
networks are key challenges in systems biology. We developed a computational method …
Profiling of discrete gynecological cancers reveals novel transcriptional modules and common features shared by other cancer types and embryonic stem cells
Studies on individual types of gynecological cancers (GCs), utilizing novel expression
technologies, have revealed specific pathogenetic patterns and gene markers for cervical …
technologies, have revealed specific pathogenetic patterns and gene markers for cervical …
Efficient test and visualization of multi-set intersections
Identification of sets of objects with shared features is a common operation in all disciplines.
Analysis of intersections among multiple sets is fundamental for in-depth understanding of …
Analysis of intersections among multiple sets is fundamental for in-depth understanding of …
GSEA-InContext: identifying novel and common patterns in expression experiments
Abstract Motivation Gene Set Enrichment Analysis (GSEA) is routinely used to analyze and
interpret coordinate pathway-level changes in transcriptomics experiments. For an …
interpret coordinate pathway-level changes in transcriptomics experiments. For an …
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures
Abstract For the Library of Integrated Network-based Cellular Signatures (LINCS) project
many gene expression signatures using the L1000 technology have been produced. The …
many gene expression signatures using the L1000 technology have been produced. The …
Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women
D Colak, A Nofal, AB AlBakheet, M Nirmal, H Jeprel… - PloS one, 2013 - journals.plos.org
Breast cancer in young women is more aggressive with a poorer prognosis and overall
survival compared to older women diagnosed with the disease. Despite recent research, the …
survival compared to older women diagnosed with the disease. Despite recent research, the …
MetSigDis: a manually curated resource for the metabolic signatures of diseases
Complex diseases cannot be understood only on the basis of single gene, single mRNA
transcript or single protein but the effect of their collaborations. The combination …
transcript or single protein but the effect of their collaborations. The combination …