Both age-related hearing loss (ARHL) and age-related loss in vestibular function (ARVL) are
prevalent conditions with deleterious consequences on the health and quality of life. Age …

Current estimates suggest that nearly half a billion people worldwide are affected by hearing
loss. Because of the major psychological, social, economic, and health ramifications …

To the Editor—Biologists are important stakeholders in genomic data, both as data
generators and as users of genomic data resources. Tools to efficiently visualize and …

Hereditary hearing loss is both clinically and genetically very heterogeneous. Despite the
large number of genes that have been associated with the condition, many cases remain …

Non-coding RNAs (ncRNAs) play a critical role in the entire body, and their mis-regulation is
often associated with disease. In parallel with the advances in high-throughput sequencing …

Long noncoding RNA (lncRNA) disorder has been found in many kinds of age‐associated
diseases. However, the role of lncRNA in the development of age‐related hearing loss …

The age of sequencing has provided unprecedented insights into the human genome. The
coding region of the genome comprises nearly 20,000 genes, of which approximately 4000 …

In recent years, there has been increased focus on exploring the role the non-protein-coding
genome plays in Mendelian disorders. One class of particular interest is long non-coding …

The inner ear is a complex structure responsible for hearing and balance, and organ
pathology is associated with deafness and balance disorders. To evaluate the role of …

Epilepsy, deafness, onychodystrophy, osteodystrophy and intellectual disability are
associated with a spectrum of mutations of human TBC1D24. The mechanisms underlying …