SM Meier-Menches, C Gerner, W Berger… - Chemical Society …, 2018 - pubs.rsc.org
Anticancer metallodrugs based on ruthenium and osmium are among the most investigated and advanced non-platinum metallodrugs. Inorganic drug discovery with these agents has …
The clinical success of the platinum-based chemotherapeutic agents has prompted the investigation of coordination and organometallic complexes of alternative metal centers for …
MM Kasprzak, A Erxleben, J Ochocki - Rsc Advances, 2015 - pubs.rsc.org
Flavonoids are widely occurring polyphenol compounds of plant origin with multiple biological and chemical activities. Due to the presence of carbonyl and hydroxyl groups they …
This review provides an introduction into the fascinating area of organometallic anticancer compounds. Although the subject dates back many years, it has witnessed considerable …
Ruthenium complexes exhibit a broad variety of biological and biomedical activities including anticancer efficiency. The reason is that the octahedral bonding of both Ru (II) and …
K Lin, ZZ Zhao, HB Bo, XJ Hao, JQ Wang - Frontiers in Pharmacology, 2018 - frontiersin.org
Ruthenium complexes are a new generation of metal antitumor drugs that are currently of great interest in multidisciplinary research. In this review article, we introduce the …
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
Interest in the medicinal properties of ruthenium (II)–arene compounds has grown rapidly over the last decade. In this account we describe the origins of the field and subsequently …
The unique properties of transition metal complexes, such as environment-responsive ligand exchange kinetics, diverse photochemical and photophysical properties, and the …