The Design, Synthesis and in vitro Evaluation of Proteolysis Targeting Chimeras (PROTACs) for the Degradation of Protein Arginine Methyltransferase 1
P Martin - 2024 - repository.cam.ac.uk
Abstract Protein arginine methyltransferase 1 (PRMT1) is a protein responsible for the
asymmetric dimethylation of arginine. PRMT1 is upregulated in a wide range of cancers and …
asymmetric dimethylation of arginine. PRMT1 is upregulated in a wide range of cancers and …
Dual Role of the Arylating Agent in a Highly C (2)-Selective Pd-Catalysed Functionalisation of Pyrrole Derivatives
M Petkovic, M Jovanovic, P Jovanovic, M Simic… - …, 2022 - thieme-connect.com
Pyrrole derivatives with C (2)-aryl substituents are an important and widespread class of
heterocyclic compounds. Their synthesis can be accomplished using several strategic …
heterocyclic compounds. Their synthesis can be accomplished using several strategic …
Toward Greener Syntheses of Pyrrole-Based Heteroaromatic Compounds using Palladium-Catalyzed Decarboxylative Cross-Coupling Reactions
C Buonomano - 2022 - spectrum.library.concordia.ca
Our daily lives depend heavily on industrial chemicals; however, this process often results in
a greater level of pollution and toxic contamination. It is of extreme importance to chemists to …
a greater level of pollution and toxic contamination. It is of extreme importance to chemists to …
Synthesis of sulfenyl dipyrroles via reaction of α-free pyrroles with thionyl chloride
MHR Beh, CD Smith, KN Robertson… - Canadian Journal of …, 2021 - cdnsciencepub.com
Sulfenyl dipyrroles feature two pyrroles linked via a sulfenyl bridge. The synthesis of sulfenyl
dipyrroles has typically involved SCl2 as the sulfur source. However, SCl2 is no longer …
dipyrroles has typically involved SCl2 as the sulfur source. However, SCl2 is no longer …
[引用][C] Bacteriochlorin syntheses-Status, problems, and exploration
Bacteriochlorins–Nature's near-infrared (NIR) chromophores–are distinguished by an
intense (𝜀∼; 105 M− 1 cm− 1) long-wavelength absorption band in the∼; 700–1000 nm …
intense (𝜀∼; 105 M− 1 cm− 1) long-wavelength absorption band in the∼; 700–1000 nm …
[引用][C] Synthesis of 2-aryl Pyrroles, Prodigiosene F-BODIPYs and B-ring Modified Prodigiosenes
SM Greening - 2019