Administration of substances directly into the cerebrospinal fluid (CSF) that surrounds the
brain and spinal cord is one approach that can circumvent the blood-brain barrier to enable …

Huntington's disease is a genetic neurodegenerative disorder. White matter alterations have
recently been identified as a relevant pathophysiological feature of Huntington's disease, but …

Among the myeloid cells in the central nervous system (CNS) microglia are the main
representatives of the innate immune system. Microglial fulfil tasks beyond phagocytosing …

Delivery of biologics via cerebrospinal fluid (CSF) has demonstrated potential to access the
tissues of the central nervous system (CNS) by circumventing the blood‐brain barrier and …

Brain cell structure is a key determinant of neural function that is frequently altered in
neurobiological disorders. Following the global loss of blood flow to the brain that initiates …

Along with the increased knowledge about the positive health effects of food bioactives, the
eating habits of many individuals have changed to obtain higher nutritional benefits from …

Parkinson disease has traditionally been classified as a movement disorder, despite
patients' accounts of diverse symptoms stemming from impairments in numerous body …

While spatial transcriptomics offer valuable insights into gene expression patterns within the
spatial context of tissue, many technologies do not have a single-cell resolution. Here, we …

Dorsal root ganglia (DRG), trigeminal ganglia (TG), other sensory ganglia, and autonomic
ganglia may be injured by some test article classes, including anti-neoplastic …

Translational research in neurological and psychiatric diseases is a rapidly advancing field
that promises to redefine our approach to these complex conditions [1–9]. The Topic …