Macrophages modulate fibrosis during newt lens regeneration

G Tsissios, A Sallese, JR Perez-Estrada… - Stem Cell Research & …, 2024 - Springer
Background Previous studies have suggested that macrophages are present during lens
regeneration in newts, but their role in the process is yet to be elucidated. Methods Here we …

Neural dependency in wound healing and regeneration

A Noble, R Qubrosi, S Cariba, K Favaro… - Developmental …, 2024 - Wiley Online Library
In response to injury, humans and many other mammals form a fibrous scar that lacks the
structure and function of the original tissue, whereas other vertebrate species can …

Characterizing the lens regeneration process in Pleurodeles waltl

G Tsissios, G Theodoroudis-Rapp, W Chen, A Sallese… - Differentiation, 2023 - Elsevier
Background Aging and regeneration are heavily linked processes. While it is generally
accepted that regenerative capacity declines with age, some vertebrates, such as newts, can …

OCTSharp: an open-source and real-time OCT imaging software based on C

W Chen, H Wang - Biomedical Optics Express, 2023 - opg.optica.org
Optical coherence tomography (OCT) demands massive data processing and real-time
displaying during high-speed imaging. Current OCT imaging software is predominantly …

[HTML][HTML] The miRNA-34a/Sirt1/p53 pathway in a rat model of lens regeneration

X Bi, R Wang, H Song, Y Wang, P Hao… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background There are many molecular factors involved in Wolffian and corneal lens
regeneration, but few in lens regeneration by lens epithelial cells (LECs) in mammals. Silent …

In vivo and ex vivo view of newt lens regeneration

G Tsissios, A Sallese, W Chen, A Miller, H Wang… - … : Methods and Protocols, 2022 - Springer
Lens regeneration in the adult newt illustrates a unique example of naturally occurring cell
transdifferentiation. During this process, iris pigmented epithelial cells (iPECs) reprogram …

Two is not necessarily better than one: A double lens in a pre‐metamorphic adult axolotl (Ambystoma mexicanum)

LH Smith, SA Park, J Gjeltema… - Veterinary …, 2023 - Wiley Online Library
An 8‐year‐old female pre‐metamorphic axolotl (Ambystoma mexicanum) was examined for
a suspected anterior lens luxation. Slit‐lamp biomicroscopy revealed two lens‐like …

[PDF][PDF] Development of a ZRS Reporter System for the Newt (Cynops pyrrhogaster) during Terrestrial Limb Regeneration

MM Casco-Robles, R Ikeda, F Maruo, C Chiba - 2024 - preprints.org
Newts, a type of urodele amphibian, offer remarkable insights into regenerative medicine
due to their extraordinary tissue regeneration capabilities—a challenging feat in humans …

Time-gated diffuse optical spectroscopy: experiments on layered media

CB McMaster - 2022 - rave.ohiolink.edu
Propagation of near-infrared light through tissues is characterized by scattering (μ s′) and
absorption (μ a). Using diffuse optical spectroscopy measurements, μ s' and μ a can be …

Regenerative hallmarks of aging: Insights through the lens of Pleurodeles waltl

G Tsissios, G Theodoroudis-Rapp, W Chen, A Sallese… - bioRxiv, 2022 - biorxiv.org
Background Aging and regeneration are heavily linked processes. While it is generally
accepted that regenerative capacity declines with age, some vertebrates, such as newts, can …