Emergence of SARS‐CoV‐2 variants warrants sustainable efforts to upgrade both the
diagnostic and therapeutic protocols. Understanding the details of cellular and molecular …

Exosomes are a subset of extracellular vesicles produced by all cells, and they are present
in various body fluids. Exosomes play crucial roles in tumor initiation/progression, immune …

The endolysosomal system is present in all cell types. Within these cells, it performs a series
of essential roles, such as trafficking and sorting of membrane cargo, intracellular signaling …

Although the identification of numerous genes involved in neurodevelopmental disorders
(NDDs) has reshaped our understanding of their etiology, there are still major obstacles in …

Phosphatidylinositol 4-kinase IIα (PI4KIIα) generates essential phospholipids and is a cargo
for endosomal adaptor proteins. Activity-dependent bulk endocytosis (ADBE) is the …

Synaptic vesicle (SV) release probability (Pr), determines the steady state and plastic control
of neurotransmitter release. However, how diversity in SV composition arises and regulates …

Ketamine is clinically used fast-acting antidepressant. Its metabolite hydroxynorketamine
(HNK) shows a robust antidepressant effect in animal studies. It is unclear, how these …

C-terminal binding proteins (CtBP) are transcriptional co-repressors regulating gene
expression. CtBP promote neuronal survival through repression of pro-apoptotic genes, and …

The extreme length of neuronal processes poses a challenge for synapse-to-nucleus
communication. In response to this challenge several different mechanisms have evolved in …

The mechanisms of angiotensin II (Ang II) on regulating adipogenic differentiation and
function remain unknown. In this study, we focus on revealing the role of C-terminal-binding …