The discovery of somatic cell nuclear transfer proved that somatic cells can carry the same
genetic code as the zygote, and that activating parts of this code are sufficient to reprogram …

The production of induced pluripotent stem cells (iPSCs) represent a breakthrough in
regenerative medicine, providing new opportunities for understanding basic molecular …

Background Human induced pluripotent stem cells (iPSCs) are expected to be useful for
regenerative medicine for many diseases. Many researchers have focused on and enabled …

The power of human induced pluripotent stem cell (hiPSC)-based studies to resolve the
smaller effects of common variants within the size of cohorts that can be realistically …

Stem cell research endeavors to generate specific subtypes of classically defined" cell
types." Here, we generate> 90% pure human artery or vein endothelial cells from pluripotent …

Chromatin accessibility is a hallmark of active regulatory regions and is functionally linked to
transcriptional networks and cell identity. However, the molecular mechanisms and networks …

Over a decade ago, a landmark study that reported derivation of induced Pluripotent Stem
Cells (iPSCs) by reprogramming fibroblasts has transformed stem cell research attracting …

The use of induced Pluripotent Stem Cells (iPSC) as a source of autologous tissues shows
great promise in regenerative medicine. Nevertheless, several major challenges remain to …

More than a decade ago, a pioneering study reported generation of induced Pluripotent
Stem Cells (iPSCs) by ectopic expression of a cocktail of reprogramming factors in …

Primary failure of eruption (PFE) is a rare disorder defined as incomplete tooth eruption
despite the presence of a clear eruption pathway. PFE is known to be caused by rare …