Background—Chagas disease remains a significant public health issue and a major cause
of morbidity and mortality in Latin America. Despite nearly 1 century of research, the …

Chagas disease (CD) is caused by the infection with the protozoan haemoflagellate
Trypanosoma cruzi. This disease is still a great menace to public health, and is largely …

One-third of all Trypanosoma cruzi-infected patients eventually develop chronic Chagas'
disease cardiomyopathy (CCC), a particularly lethal inflammatory dilated cardiomyopathy …

Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a
critical lack of methods for prevention of infection or treatment of acute infection and chronic …

Background Myocardium damage during Chagas' disease results from the immunological
imbalance between pro-and production of anti-inflammatory cytokines and has been …

We compared plasma tumor necrosis factor-alpha (TNF-alpha) levels among asymptomatic/"
indeterminate" Chagas disease patients (ASY) and patients across the clinical spectrum of …

The pathogenesis of Chagas disease cardiomyopathy (CCC) is not well understood. Since
studies show that myocarditis is more frequent during the advanced stages of the disease …

Chagas disease is caused by the flagellate protozoan Trypanosoma cruzi, affecting millions
of people throughout Latin America. The parasite dampens host immune response causing …

Chagas' disease is a major health problem in Latin America, where it constitutes one of the
leading causes of heart failure. About one fourth of Trypanosoma cruzi-infected individuals …

Chagas disease continues to be a significant public health problem, as ca. 10 million people
are still infected with T. cruzi in Latin America. Decades after primary infection, 30% of …