Bone health in patients with dyslipidemias: an underestimated aspect

P Anagnostis, M Florentin, S Livadas… - International Journal of …, 2022 - mdpi.com
Beyond being aging-related diseases, atherosclerosis and osteoporosis share common
pathogenetic pathways implicated in bone and vascular mineralization. However, the …

Lipid metabolism within the bone micro-environment is closely associated with bone metabolism in physiological and pathophysiological stages

B Wang, H Wang, Y Li, L Song - Lipids in Health and Disease, 2022 - Springer
Recent advances in society have resulted in the emergence of both hyperlipidemia and
obesity as life-threatening conditions in people with implications for various types of …

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

SFA Grant, G Thorleifsson, I Reynisdottir… - Nature …, 2006 - nature.com
We have previously reported suggestive linkage of type 2 diabetes mellitus to chromosome
10q. We genotyped 228 microsatellite markers in Icelandic individuals with type 2 diabetes …

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

V Steinthorsdottir, G Thorleifsson, I Reynisdottir… - Nature …, 2007 - nature.com
We conducted a genome-wide association study for type 2 diabetes (T2D) in Icelandic cases
and controls, and we found that a previously described variant in the transcription factor 7 …

[HTML][HTML] Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women

YH Hsu, SA Venners, HA Terwedow, Y Feng… - The American journal of …, 2006 - Elsevier
Background: Higher fat mass may be an independent risk factor for osteoporosis and
osteoporotic fractures. Objective: We aimed to determine the independent contribution of fat …

[HTML][HTML] Multiple genetic loci for bone mineral density and fractures

U Styrkarsdottir, BV Halldorsson… - … England Journal of …, 2008 - Mass Medical Soc
Background Bone mineral density influences the risk of osteoporosis later in life and is
useful in the evaluation of the risk of fracture. We aimed to identify sequence variants …

Childhood obesity, bone development, and cardiometabolic risk factors

NK Pollock - Molecular and cellular endocrinology, 2015 - Elsevier
Osteoporosis and obesity are both major public health concerns. It has long been
considered that these are distinct disorders rarely found in the same individual; however …

Association between bone mineral density and lipid profile in Chinese women

Q Zhang, J Zhou, Q Wang, C Lu, Y Xu… - … interventions in aging, 2020 - Taylor & Francis
Purpose Atherosclerotic cardiovascular disease may share the risk factors for low bone
mineral density (BMD), one of which is dyslipidemia. The association between serum …

Exendin‐4, a glucagon‐like peptide‐1 receptor agonist, prevents osteopenia by promoting bone formation and suppressing bone resorption in aged ovariectomized …

X Ma, J Meng, M Jia, L Bi, Y Zhou… - Journal of Bone and …, 2013 - academic.oup.com
Osteoporosis mainly affects postmenopausal women and older men. Gastrointestinal
hormones released after meal ingestion, such as glucose‐dependent insulinotropic peptide …

Understanding the local actions of lipids in bone physiology

A During, G Penel, P Hardouin - Progress in lipid research, 2015 - Elsevier
The adult skeleton is a metabolically active organ system that undergoes continuous
remodeling to remove old and/or stressed bone (resorption) and replace it with new bone …