Natural killer (NK) cells are lymphocytes of the innate immune system. A key feature of NK
cells is their ability to recognize a wide range of cells in distress, particularly tumour cells …

B cell and T cell receptor repertoires compose the adaptive immune receptor repertoire
(AIRR) of an individual. The AIRR is a unique collection of antigen-specific receptors that …

The accumulation of senescent cells promotes ageing and age-related diseases, but
molecular mechanisms that senescent cells use to evade immune clearance and …

Human bone marrow permanently harbors high numbers of neutrophils, and a tumor-
supportive bias of these cells could significantly impact bone marrow-confined …

Virtual patients and digital patients/twins are two similar concepts gaining increasing
attention in health care with goals to accelerate drug development and improve patients' …

Implementation of biomarkers in sepsis and septic shock in emergency situations, remains
highly challenging. This viewpoint arose from a public–private 3-day workshop aiming to …

The intestinal microbiota determines immune responses against extraintestinal antigens,
including tumor-associated antigens. Indeed, depletion or gross perturbation of the …

Natural killer (NK) cells, initially identified for their rapid virus-infected and leukemia cell
killing and tumor destruction, are pivotal in immunity. They exhibit multifaceted roles in …

Our aim is to present an updated overview of the erythrocyte metabolism highlighting its
richness and complexity. We have manually collected and connected the available …

Innate immune cells are primary effectors during host defense and in sterile inflammation.
Their production in the bone marrow is tightly regulated by growth and niche factors, and …