HLA-G has a relevant role in immune response regulation. The overall structure of the HLA-
G coding region has been maintained during the evolution process, in which most of its …

Human leukocyte antigen (HLA)-G molecule, a non-classical HLA-Ib molecule, is less
polymorphic when compared to classical HLA class I molecules. Human leukocyte antigen …

HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows
lower frequency of polymorphism at the coding region but higher variability at regulatory …

Human leukocyte antigen G (HLA-G) belongs to the family of non-classical HLA class I
genes, located within the major histocompatibility complex (MHC). HLA-G has been the …

Background HLA-G is an immune checkpoint molecule. Since a differential molecule
expression has been reported even for healthy individuals, many studies have focused on …

The human G-leukocyte antigen (HLA-G) molecule is a non-classical major
histocompatibility complex (MHC) class I molecule. The pertinence of HLA-G has been …

The immune checkpoint HLA-G prevents maternal rejection of the fetus and contributes in
cancer invasion and acceptance of allografts. The 5'and 3'regulatory regions of the HLA-G …

HLA-G is a molecule essential to the maintenance of the maternal-fetal interface tolerance,
thus contributing to a healthy pregnancy. Here we investigate the role of HLA-G single …

Reduced expression of human leukocyte antigen-G (HLA-G) has been linked to onset of
preeclampsia. Associations have also been reported between preeclampsia and single …

The HLA-G molecule presents immunomodulatory properties that might inhibit immune
responses when interacting with specific Natural Killer and T cell receptors, such as …