Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

B Liu, M Li, Z Zhou, X Guan, Y Xiang - Journal of autoimmunity, 2020 - Elsevier
The emergent outbreak of coronavirus disease 2019 (COVID-19) has caused a global
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are …

The immunology of macrophage activation syndrome

CB Crayne, S Albeituni, KE Nichols… - Frontiers in …, 2019 - frontiersin.org
Synonymous with secondary hemophagocytic lymphohistiocytosis, macrophage activation
syndrome (MAS) is a term used by rheumatologists to describe a potentially life-threatening …

The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage …

B Shakoory, A Geerlinks, M Wilejto, K Kernan… - Annals of the rheumatic …, 2023 - Elsevier
Objective Haemophagocytic lymphohistiocytosis (HLH) and macrophage activation
syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes that can …

Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome

P Mehta, RQ Cron, J Hartwell, JJ Manson… - The Lancet …, 2020 - thelancet.com
The term cytokine storm syndromes describes conditions characterised by a life-threatening,
fulminant hypercytokinaemia with high mortality. Cytokine storm syndromes can be genetic …

A comprehensive review on adult onset Still's disease

R Giacomelli, P Ruscitti, Y Shoenfeld - Journal of autoimmunity, 2018 - Elsevier
Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology
usually affecting young adults; spiking fever, arthritis and evanescent rash are commonly …

2016 classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American …

A Ravelli, F Minoia, S Davì, AC Horne… - Arthritis & …, 2016 - Wiley Online Library
Objective To develop criteria for the classification of macrophage activation syndrome (MAS)
in patients with systemic juvenile idiopathic arthritis (JIA). Methods A multistep process …

Juvenile idiopathic arthritis

A Ravelli, A Martini - The Lancet, 2007 - thelancet.com
Juvenile idiopathic arthritis is a broad term that describes a clinically heterogeneous group
of arthritides of unknown cause, which begin before 16 years of age. This term …

Recommendations for the use of etoposide-based therapy and bone marrow transplantation for the treatment of HLH: consensus statements by the HLH Steering …

S Ehl, I Astigarraga, T von Bahr Greenwood… - The Journal of Allergy …, 2018 - Elsevier
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory
syndrome requiring aggressive immunosuppressive therapy. Following 2 large international …

Development and initial validation of the MS score for diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis

F Minoia, F Bovis, S Davì, AC Horne… - Annals of the Rheumatic …, 2019 - Elsevier
Objective To develop and validate a diagnostic score that aids in identifying macrophage
activation syndrome (MAS) in patients with systemic juvenile idiopathic arthritis (sJIA) …

Macrophage activation syndrome

A Ravelli, S Davì, F Minoia, A Martini… - Hematology …, 2015 - hemonc.theclinics.com
Macrophage Activation Syndrome - Hematology/Oncology Clinics Skip to Main Content
Advertisement Hematology/Oncology Clinics Log in Register Log in Subscribe Claim Skip …