The enzymatic basis for pesticide bioremediation
Enzymes are central to the biology of many pesticides, influencing their modes of action,
environmental fates and mechanisms of target species resistance. Since the introduction of …
environmental fates and mechanisms of target species resistance. Since the introduction of …
Benzotriazole ultraviolet stabilizers show potent activities as human aryl hydrocarbon receptor ligands
H Nagayoshi, K Kakimoto, S Takagi… - … science & technology, 2015 - ACS Publications
Benzotriazole ultraviolet stabilizers (BUVSs) used in consumer products are raising
concerns as new pollutants in the aquatic environment. We determined the agonistic …
concerns as new pollutants in the aquatic environment. We determined the agonistic …
Nonylphenol algal bioaccumulation and its effect through the trophic chain
Nonylphenol is a metabolic intermediate from the microbial transformation of detergents
used worldwide. While nonylphenol shows some acute toxicity, it is also able to mimic …
used worldwide. While nonylphenol shows some acute toxicity, it is also able to mimic …
Integrated biomarker analysis of chlorpyrifos metabolism and toxicity in the earthworm Aporrectodea caliginosa
To increase our understanding about the mode of toxic action of organophosphorus
pesticides in earthworms, a microcosm experiment was performed with Aporrectodea …
pesticides in earthworms, a microcosm experiment was performed with Aporrectodea …
Ginkgo biloba extract markedly induces pentoxyresorufin O-dealkylase activity in rats
K Umegaki, K Saito, Y Kubota, H Sanada… - The Japanese Journal …, 2002 - jstage.jst.go.jp
We examined the effect of Ginkgo biloba extract (GBE) on hepatic drug-metabolizing
enzymes, particularly cytochrome P450 (CYP), in rats. Rats were fed a GBE-containing diet …
enzymes, particularly cytochrome P450 (CYP), in rats. Rats were fed a GBE-containing diet …
EROD and MROD as markers of cytochrome P450 1A activities in hepatic microsomes from entire and castrated male pigs
G Zamaratskaia, V Zlabek - Sensors, 2009 - mdpi.com
In the present study, we characterized the kinetic parameters of 7-ethoxy-resorufin O-
deethylation (EROD) and 7-methoxyresorufin O-demethylation (MROD) in hepatic …
deethylation (EROD) and 7-methoxyresorufin O-demethylation (MROD) in hepatic …
The potential acute and chronic toxicity of cyfluthrin on the soil model organism, Eisenia fetida
L Li, D Yang, Y Song, Y Shi, B Huang, A Bitsch… - … and Environmental Safety, 2017 - Elsevier
In this study, the acute (72 h and 14 d) and chronic (28 d and 8 weeks) effects of cyfluthrin on
earthworms were evaluated across different endpoints, which are mortality, growth …
earthworms were evaluated across different endpoints, which are mortality, growth …
Effects of bifenthrin exposure in soil on whole-organism endpoints and biomarkers of earthworm Eisenia fetida
In this study, toxic effects of bifenthrin in soil on earthworms were evaluated by acute and
chronic toxic endpoints combined with a set of biomarkers. Bifenthrin was moderately toxic …
chronic toxic endpoints combined with a set of biomarkers. Bifenthrin was moderately toxic …
Cytochrome P450 probe substrate metabolism kinetics in Sprague Dawley rats
JP Chovan, SC Ring, E Yu, JP Baldino - Xenobiotica, 2007 - Taylor & Francis
The objective of the current study was to investigate the metabolism of cytochrome P450
(CYP) probe substrates in male Sprague Dawley rat liver microsomes and to determine their …
(CYP) probe substrates in male Sprague Dawley rat liver microsomes and to determine their …
The reduction of the combined effects of aflatoxin and ochratoxin a in piglet livers and kidneys by dietary antioxidants
The purpose of this study was to investigate the combined effects of aflatoxin B1 and
ochratoxin A on protein expression and catalytic activities of CYP1A2, CYP2E1, CYP3A29 …
ochratoxin A on protein expression and catalytic activities of CYP1A2, CYP2E1, CYP3A29 …