Lab-on-a-chip (LOC) and organ-on-a-chip (OOC) devices are highly versatile platforms that
enable miniaturization and advanced controlled laboratory functions (ie, microfluidics …

Advanced computational techniques and mathematical modeling have become more and
more important to the study of cardiac electrophysiology. In this review, we provide a brief …

Drug-induced cardiotoxicity is a major problem in drug discovery. Many approaches to
efficient drug screening have been developed, including animal testing in vivo and cell …

The patch-clamp technique represents an electrophysiology type of method. This is one of
several insightful approaches with five major configurations, namely a loose patch, cell …

Cenobamate is a novel third-generation antiepileptic drug used for the treatment of focal
onset seizures and particularly for multi-drug-resistant epilepsy; it acts on multiple targets …

Chloroquine and hydroxychloroquine have been proposed recently as therapy for SARS-
CoV-2-infected patients, but during 3 months of extensive use concerns were raised related …

In the Hollywood blockbuster 'The Curious Case of Benjamin Button', a fantastical fable
unfolds of a man's life that travels through time reversing the aging process; as the tale …

Personalized medicine refers to the tailored application of medical treatment at an individual
level, considering the specific genotype or phenotype of each patient for targeted therapy. In …

State-of-the-art innovations in optical cardiac electrophysiology are significantly enhancing
cardiac research. A potential leap into patient care is now on the horizon. Optical mapping …

Subtype-specific human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
are promising tools, eg, to assess the potential of drugs to cause chronotropic effects (nodal …