[HTML][HTML] Osteoarthritis: a disease of the joint as an organ

RF Loeser, SR Goldring, CR Scanzello… - Arthritis and …, 2012 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is the most common form of arthritis and a major cause of pain and
disability in older adults (1). Often OA is referred to as degenerative joint disease “(DJD)” …

A systematic review of the femoral origin and tibial insertion morphology of the ACL

S Kopf, V Musahl, S Tashman, M Szczodry… - Knee Surgery, Sports …, 2009 - Springer
Transtibial single bundle anterior cruciate ligament (ACL) reconstruction has been the gold
standard for several years. This technique often fails to restore native ACL femoral origin …

Anterior cruciate ligament changes in the human knee joint in aging and osteoarthritis

A Hasegawa, S Otsuki, C Pauli, S Miyaki… - Arthritis & …, 2012 - Wiley Online Library
Objective The development and patterns of spontaneous age‐related changes in the
anterior cruciate ligament (ACL) and their relationship to articular cartilage degeneration are …

Intraarticular ligament degeneration is interrelated with cartilage and bone destruction in osteoarthritis

G Schulze-Tanzil - Cells, 2019 - mdpi.com
Osteoarthritis (OA) induces inflammation and degeneration of all joint components including
cartilage, joint capsule, bone and bone marrow, and ligaments. Particularly intraarticular …

Size variability of the human anterior cruciate ligament insertion sites

S Kopf, MW Pombo, M Szczodry… - … American journal of …, 2011 - journals.sagepub.com
Background: Current trends in anterior cruciate ligament reconstruction (ACLR) have been
toward anatomical reconstruction that restores the normal size and location of the anterior …

Mechanisms of quadriceps muscle weakness in knee joint osteoarthritis: the effects of prolonged vibration on torque and muscle activation in osteoarthritic and healthy …

DA Rice, PJ McNair, GN Lewis - Arthritis research & therapy, 2011 - Springer
Introduction A consequence of knee joint osteoarthritis (OA) is an inability to fully activate the
quadriceps muscles, a problem termed arthrogenic muscle inhibition (AMI). AMI leads to …

Tendons and ligaments: connecting developmental biology to musculoskeletal disease pathogenesis

H Asahara, M Inui, MK Lotz - Journal of Bone and Mineral …, 2017 - academic.oup.com
Tendons and ligaments provide connections between muscle and bone or bone and bone
to enable locomotion. Damage to tendons and ligaments caused by acute or chronic injury …

Multiple injections of leukoreduced platelet rich plasma reduce pain and functional impairment in a canine model of ACL and meniscal deficiency

JL Cook, PA Smith, CC Bozynski… - Journal of …, 2016 - Wiley Online Library
Platelet rich plasma (PRP) is used to treat many musculoskeletal disorders. We used a
canine model to determine the effects of multiple intra‐articular injections of leukoreduced …

Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis

A Hasegawa, H Nakahara, M Kinoshita… - Arthritis research & …, 2013 - Springer
Introduction Anterior cruciate ligament (ACL) degeneration is observed in most osteoarthritis
(OA)-affected knee joints. However, the specific spatial and temporal relations of these …

Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review

AE Peters, R Akhtar, EJ Comerford, KT Bates - PeerJ, 2018 - peerj.com
Understanding how structural and functional alterations of individual tissues impact on
whole-joint function is challenging, particularly in humans where direct invasive …