[HTML][HTML] Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

[HTML][HTML] The immune microenvironment in cartilage injury and repair

M Li, H Yin, Z Yan, H Li, J Wu, Y Wang, F Wei, G Tian… - Acta Biomaterialia, 2022 - Elsevier
The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

[HTML][HTML] Antibacterial conductive self-healing hydrogel wound dressing with dual dynamic bonds promotes infected wound healing

L Qiao, Y Liang, J Chen, Y Huang, SA Alsareii… - Bioactive materials, 2023 - Elsevier
In clinical applications, there is a lack of wound dressings that combine efficient resistance to
drug-resistant bacteria with good self-healing properties. In this study, a series of adhesive …

[HTML][HTML] Harnessing strategies for enhancing diabetic wound healing from the perspective of spatial inflammation patterns

Y Cai, K Chen, C Liu, X Qu - Bioactive Materials, 2023 - Elsevier
Diabetic wound is a great threat to patient's health and lives. The refractory diabetic wound
shows spatial inflammation patterns, in which the early-wound pattern depicts a deprived …

[HTML][HTML] Modulating macrophage activities to promote endogenous bone regeneration: Biological mechanisms and engineering approaches

Y Niu, Z Wang, Y Shi, L Dong, C Wang - Bioactive materials, 2021 - Elsevier
A coordinated interaction between osteogenesis and osteoimmune microenvironment is
essential for successful bone healing. In particular, macrophages play a central regulatory …

Control of innate immune response by biomaterial surface topography, energy, and stiffness

JO Abaricia, N Farzad, TJ Heath, J Simmons… - Acta Biomaterialia, 2021 - Elsevier
As the focus of implantable biomaterials has shifted from bioinert implants to bioactive
designs, recent research has highlighted the complex interactions between cell physiologic …

Mesenchymal stromal exosome–functionalized scaffolds induce innate and adaptive immunomodulatory responses toward tissue repair

N Su, Y Hao, F Wang, W Hou, H Chen, Y Luo - Science advances, 2021 - science.org
Designing scaffolds capable of inducing and guiding appropriate immune responses holds
promise for tissue repair/regeneration. Biofunctional scaffolds were here prepared by …

[HTML][HTML] Functional regeneration and repair of tendons using biomimetic scaffolds loaded with recombinant periostin

Y Wang, S Jin, D Luo, D He, C Shi, L Zhu… - Nature …, 2021 - nature.com
Tendon injuries disrupt the balance between stability and mobility, causing compromised
functions and disabilities. The regeneration of mature, functional tendons remains a clinical …

Macrophage polarization in THP-1 cell line and primary monocytes: A systematic review

ZNM Yasin, FNM Idrus, CH Hoe, GB Yvonne-Tee - Differentiation, 2022 - Elsevier
Macrophages derived from human monocytic leukemia THP-1 cell line are often used as the
alternative of human primary macrophage. However, the polarization method of THP-1 to …

The role of biomaterials and scaffolds in immune responses in regenerative medicine: macrophage phenotype modulation by biomaterial properties and scaffold …

E Antmen, NE Vrana, V Hasirci - Biomaterials science, 2021 - pubs.rsc.org
Scaffolds are an integral part of the regenerative medicine field. The contact of biomaterials
with tissue, as was clearly observed over the years, induces immune reactions in a material …