Genome variation and population structure among 1142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii

CS Clarkson, A Miles, NJ Harding, ER Lucas… - Genome …, 2020 - genome.cshlp.org
Mosquito control remains a central pillar of efforts to reduce malaria burden in sub-Saharan
Africa. However, insecticide resistance is entrenched in malaria vector populations, and …

Genome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and Anopheles coluzzii

ER Lucas, SC Nagi, A Egyir-Yawson… - Nature …, 2023 - nature.com
Resistance to insecticides in Anopheles mosquitoes threatens the effectiveness of malaria
control, but the genetics of resistance are only partially understood. We performed a large …

Seaweed Sargassum wightii mediated preparation of TiO2 nanoparticles, larvicidal activity against malaria and filariasis vectors, and its effect on non-target organisms

D Mathivanan, C Kamaraj, SR Suseem… - Environmental …, 2023 - Elsevier
Malaria and Lymphatic filariasis are considered significant public health concerns in several
countries. As a researcher, controlling those mosquitos using safe and eco-friendly …

Mapping trends in insecticide resistance phenotypes in African malaria vectors

PA Hancock, CJM Hendriks, JA Tangena, H Gibson… - PLoS …, 2020 - journals.plos.org
Mitigating the threat of insecticide resistance in African malaria vector populations requires
comprehensive information about where resistance occurs, to what degree, and how this …

The genetic architecture of target‐site resistance to pyrethroid insecticides in the African malaria vectors Anopheles gambiae and Anopheles coluzzii

CS Clarkson, A Miles, NJ Harding… - Molecular …, 2021 - Wiley Online Library
Resistance to pyrethroid insecticides is a major concern for malaria vector control.
Pyrethroids target the voltage‐gated sodium channel (VGSC), an essential component of the …

Agrigenomic Diversity Unleashed: Current Single Nucleotide Polymorphism Genotyping Methods for the Agricultural Sciences

RD Lawrie, SE Massey - Applied Biosciences, 2023 - mdpi.com
Single Nucleotide Polymorphisms (SNPs) are variations that occur at single nucleotides in
the genome and are present at an appreciable level in a population. SNPs can be linked to …

CRISPR/Cas9 modified An. gambiae carrying kdr mutation L1014F functionally validate its contribution in insecticide resistance and combined effect with metabolic …

L Grigoraki, R Cowlishaw, T Nolan, M Donnelly… - PLoS …, 2021 - journals.plos.org
Insecticide resistance in Anopheles mosquitoes is a major obstacle in maintaining the
momentum in reducing the malaria burden; mitigating strategies require improved …

A next generation targeted amplicon sequencing method to screen for insecticide resistance mutations in Aedes aegypti populations reveals a rdl mutation in …

EL Collins, JE Phelan, M Hubner… - PLoS neglected …, 2022 - journals.plos.org
Aedes mosquito vectors transmit many viruses of global health concern, including dengue,
chikungunya and Zika. These vector-borne viral diseases have a limited number of …

Integration of whole genome sequencing and transcriptomics reveals a complex picture of the reestablishment of insecticide resistance in the major malaria vector …

VA Ingham, JA Tennessen, ER Lucas, S Elg… - PLoS …, 2021 - journals.plos.org
Insecticide resistance is a major threat to gains in malaria control, which have been stalling
and potentially reversing since 2015. Studies into the causal mechanisms of insecticide …

Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo

TPW Dennis, P Pescod, S Barasa, LT Cerdeira… - Scientific Reports, 2024 - nature.com
Abstract The Democratic Republic of Congo (DRC) suffers from one of the highest malaria
burdens worldwide, but information on its Anopheles vector populations is relatively limited …