The landscape of histone modifications in epigenomics since 2020

M Shirvaliloo - Epigenomics, 2022 - Taylor & Francis
Histone proteins are a primary component of chromatin; therefore, any modifications to their
structure are anticipated to affect the behavior of our genetic material, which is manifested in …

Artificial intelligence and deep learning algorithms for epigenetic sequence analysis: A review for epigeneticists and AI experts

M Tahir, M Norouzi, SS Khan, JR Davie… - Computers in Biology …, 2024 - Elsevier
Epigenetics encompasses mechanisms that can alter the expression of genes without
changing the underlying genetic sequence. The epigenetic regulation of gene expression is …

Prediction of gene expression using histone modification patterns extracted by Particle Swarm Optimization

NB Paul, JC Wolber, ML Sahrhage, T Beißbarth… - …, 2025 - academic.oup.com
Motivation Histone modifications play an important role in transcription regulation. Although
the general importance of some histone modifications for transcription regulation has been …

Predicting the effect of CRISPR-Cas9-based epigenome editing

SS Batra, A Cabrera, JP Spence, J Goell, SS Anand… - …, 2024 - pmc.ncbi.nlm.nih.gov
Epigenetic regulation orchestrates mammalian transcription, but functional links between
them remain elusive. To tackle this problem, we use epigenomic and transcriptomic data …

Simulating cell-free chromatin using preclinical models for cancer-specific biomarker discovery

SD De Michino, SC Main, L Penny, R Kridel… - bioRxiv, 2023 - biorxiv.org
Cell-free chromatin (cf-chromatin) is a rich source of biomarkers across various conditions,
including cancer. Tumor-derived circulating cf-chromatin can be profiled for epigenetic …

[PDF][PDF] TransformerChrome: Transformer-based Model for Prediction of Gene Expression from Histone Modifications

M Tahir, S Khan, J Davie, S Yamanaka… - Proc. Can. Conf. Artif …, 2024 - assets.pubpub.org
Epigenetic mechanisms play a crucial role in regulating the expression of genes affecting
the development, growth, and functioning of organisms, ensuring the activation or …

Deep Learning Models For Biomedical Data Analysis

L Nwosu - 2023 - digitalcommons.pvamu.edu
The field of biomedical data analysis is a vibrant area of research dedicated to extracting
valuable insights from a wide range of biomedical data sources, including biomedical …

Epigenetic Responses of Arabidopsis to Abiotic Stress

SR Laliberte - 2023 - vtechworks.lib.vt.edu
Weed resistance to control measures, particularly herbicides, is a growing problem in
agriculture. In the case of herbicides, resistance is sometimes connected to genetic changes …