In humans, mitochondria play key roles in the regulation of cellular functions, such as the
regulation of the innate immune response and are targets of several pathogenic viruses and …

Mitochondria, responsible for cellular energy synthesis and signal transduction, intricately
regulate diverse metabolic processes, mediating fundamental biological phenomena such …

Background Mitochondrial participation in tumorigenesis and metastasis has been studied
for many years, but several aspects of this mechanism remain unclear, such as the …

Mitochondrial DNA (mtDNA) mutations contribute to human disease across a range of
severity, from rare, highly penetrant mutations causal for monogenic disorders to mutations …

Background Gastric cancer (GC) ranks among the most common malignancies worldwide.
This study aimed to find critical genes/pathways in GC pathogenesis. Methods Gene …

Objective Monoamine oxidase A (MAO-A) is a mitochondrial protein involved in
tumourigenesis in different types of cancer. However, the biological function of MAO-A in …

Background In recent years, the mitochondria/immune system interaction has been
proposed, so that variants of mitochondrial genome and levels of heteroplasmy might …

Leprosy is a chronic bacterial infection mainly caused by Mycobacterium leprae that
primarily affects skin and peripheral nerves. Due to its ability to absorb carbon from the host …

Background Emerging evidence confirms that lncRNAs (long non-coding RNAs) are
potential biomarkers that play vital roles in tumors. ZNF582-AS1 is a novel lncRNA that …

Next-generation sequencing (NGS) applications have flourished in the last decade,
permitting the identification of cancer driver genes and profoundly expanding the …